Evidence map›Paper›PMID 27436098›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2016

Combination of ECMO and cytokine adsorption therapy for severe sepsis with cardiogenic shock and ARDS due to Panton-Valentine leukocidin-positive Staphylococcus aureus pneumonia and H1N1.

N J Lees, Ajp Rosenberg, A I Hurtado-Doce, J Jones, N Marczin, M Zeriouh, A Weymann, A Sabashnikov, A R Simon, A F Popov

Abstract readCase Reports
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In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

N J LeesDepartment of Anaesthetic and Critical Care, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK. n.lees@rbht.nhs.uk.
Ajp RosenbergDepartment of Anaesthetic and Critical Care, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
A I Hurtado-DoceDepartment of Anaesthetic and Critical Care, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
J JonesDepartment of Anaesthetic and Critical Care, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
N MarczinImperial College, London, UK.
M ZeriouhDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
A WeymannDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
A SabashnikovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK. a.sabashnikov@gmail.com.
A R SimonDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
A F PopovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Royal Brompton & Harefield NHS Foundation Trust, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
Royal Brompton & Harefield NHS Foundation Trust · GBHarefield Hospital · GBImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced cardiogenic shock in combination with severe acute respiratory failure represents a life-threatening combination that is often refractory to the conventional methods of treatment. We describe the case of a 33-year-old patient who developed acute cardiovascular collapse and ARDS secondary to superinfection of Panton-Valentine leukocidin-positive Staphylococcus aureus and H1N1 pneumonia who underwent successful combination therapy for severe sepsis-related cardiomyopathy and respiratory failure using extracorporeal membrane oxygenation and cytokine adsorption therapy.

Indexed as

Extracorporeal Membrane OxygenationHemoperfusionAdsorptionAdultBacterial ToxinsCytokinesExotoxinsFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLeukocidinsPneumonia, StaphylococcalRespiratory Distress SyndromeRespiratory InsufficiencySepsisBacterial ToxinsCytokinesExotoxinsLeukocidinsPanton-Valentine leukocidinAdsorption therapyCytokinesExtracorporeal membrane oxygenation (ECMO)H1N1Sepsis

Identifiers

PMID27436098
OpenAlexW2486087329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.