Evidence map›Paper›PMID 27436053›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2016

The Genetic and Environmental Association Between Parental Monitoring and Risk of Cannabis, Stimulants, and Cocaine Initiation in a Sample of Male Twins: Does Parenting Matter?

Emily L Olivares, Kenneth S Kendler, Michael C Neale, Nathan A Gillespie

Abstract readTwin Study
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Environmental, genetic and epigenetic contributions to cocaine addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily L OlivaresVirginia Institute for Psychiatric and Behavior Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Kenneth S KendlerVirginia Institute for Psychiatric and Behavior Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Michael C NealeVirginia Institute for Psychiatric and Behavior Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Nathan A GillespieVirginia Institute for Psychiatric and Behavior Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.

Funding

Psychometric and Genetic Assessments of Substance UseR37DA018673 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEALE, MICHAEL CHURTON · 2005 to 2014
$3.7M
Psychometric and Genetic Assessments of Substance UseR01DA018673 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEALE, MICHAEL CHURTON · 2004 to 2019
$2.3M
Genetic Epideniologic Models of Alcohol AbuseR37AA007728 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1998 to 2007
$2.2M
Genetic & environmental pathways to drug use, abuse & dependenceR00DA023549 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI GILLESPIE, NATHAN ALEXANDER · 2010 to 2012
$717k
PERSISTENCE &CHANGE IN DRINKING HABITS: TWIN STUDYR01AA007535 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1989 to 1996
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NATURAL HISTORY OF ALCOHOL USE &ABUSE--GENETIC MODELSR01AA007728 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1988 to 1998
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NIAAA NIH HHS R01 AA007535NIAAA NIH HHS R01 AA007728NIAAA NIH HHS R37 AA007728NIDA NIH HHS R00 DA023549NIDA NIH HHS R01 DA018673NIDA NIH HHS R37 DA018673
6 · The paper itself

Abstract

Our aim was to test the direction of causation between self-report parental monitoring (PM) and the liability to illicit drug initiation (DI) as indicated by cannabis, cocaine, and stimulants. We fitted a multiple indicator model to test causal and non-causal models based on a large, genetically informative cross-sectional sample of male twins. The sample comprised 1,778 males aged 24-62 years from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. Data came from self-report measures of lifetime cannabis, stimulants, and cocaine initiation, and retrospective assessment of PM between ages 8-17 years. Multivariate modeling showed that familial aggregation in PM and DI were both explained by a combination of additive genetic and shared environmental effects. Moreover, the significant association between PM and DI was best explained by a correlated liability model versus causal models. PM has typically been assumed to be an environmental, causal risk factor for drug use and has been shown to be among the more salient environmental risk factors for illicit DI. Our data were not consistent with this causal hypothesis. Instead, a correlated liability model in which PM and risk of DI share common genetic and environmental risks provided a better fit to the data.

Indexed as

Cocaine-Related DisordersMarijuana AbuseParentingAdolescentAdultChildHumansMaleMethylphenidateMiddle AgedModels, TheoreticalMultivariate AnalysisSubstance-Related DisordersMethylphenidatecannabiscausalitycocaineparental monitoringparentingstimulants

Identifiers

PMID27436053
PMCPMC4972338

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.