Evidence map›Paper›PMID 27435706›Full record

ReviewImmunologic research2017

Autoimmune reaction after anti-tetanus vaccination-description of four cases and review of the literature.

N Ruhrman-Shahar, J Torres-Ruiz, P Rotman-Pikielny, Y Levy

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Bodily distress syndrome after receiving vaccines: A case report.Journal of general and family medicine · 2019
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

N Ruhrman-ShaharDepartment of Medicine E, Meir Medical Center, Kfar-Saba (Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel), 44261, Kfar-Saba, Israel.
J Torres-RuizDepartment of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
P Rotman-PikielnyDepartment of Medicine E, Meir Medical Center, Kfar-Saba (Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel), 44261, Kfar-Saba, Israel.
Y LevyDepartment of Medicine E, Meir Medical Center, Kfar-Saba (Affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel), 44261, Kfar-Saba, Israel. levy.yair@clalit.org.il.
Meir Medical Center · ILInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune reaction after vaccination is sporadically reported in the medical literature. Vaccinations are generally safe and have an important role in eradicating endemic diseases worldwide. Nevertheless, the question arises as to whether there is a possibility of post-vaccination autoimmune phenomena. The anti-tetanus vaccine is being used since 1924, and it is part of the recommended immunization schedules for children. There are few reports of autoimmune diseases, such as rheumatoid arthritis and anti-phospholipid syndrome after anti-tetanus vaccination. Herein, we describe four cases, of which we believe, show a clear temporal relation between anti-tetanus vaccination and the appearance of dermatomyositis, systemic lupus erythematosus, type 1 diabetes mellitus and anti-phospholipid syndrome. We also suggest some of the pathogenic mechanisms that promote a pathogenic autoimmune response.

Indexed as

AdolescentAdultAutoimmune DiseasesAutoimmunityFemaleHumansMaleMiddle AgedTetanus ToxoidVaccinationTetanus ToxoidAnti-phospholipid syndromeAnti-tetanus vaccineASIAAutoimmune reactionDermatomyositisSystemic lupus erythematosusType 1 diabetes mellitusVaccination

Identifiers

PMID27435706
OpenAlexW2489598213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.