Evidence map›Paper›PMID 27435590›Full record

ReviewEndocrine2017

Pituitary magnetic resonance imaging in Cushing's disease.

Giovanni Vitale, Fabio Tortora, Roberto Baldelli, Francesco Cocchiara, Rosa Maria Paragliola, Emilia Sbardella, Chiara Simeoli, Ferdinando Caranci, Rosario Pivonello, Annamaria Colao and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. MRI for Cushing Disease: A Systematic Review.AJNR. American journal of neuroradiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Giovanni VitaleDepartment of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy. giovanni.vitale@unimi.it.ORCID http://orcid.org/0000-0003-2478-683X
Fabio TortoraDipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale "F. Magrassi e A. Lanzara", Second University of Naples, Naples, Italy.
Roberto BaldelliUOSD Endocrinologia, Istituto Nazionale Tumori "Regina Elena" -Roma, Rome, Italy.
Francesco CocchiaraEndocrinology, Department of Internal Medicine and Medical Specialities (DiMI), IRCCS AOU San Martino-IST, University of Genova, Genova, Italy.
Rosa Maria ParagliolaEndocrinology, Università Cattolica del Sacro Cuore, Rome, Italy.
Emilia SbardellaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Chiara SimeoliDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy.
Ferdinando CaranciDepartment of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Rosario PivonelloDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy.
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples, Italy.
A.B.C. Group
University of Naples Federico II · ITUniversità Cattolica del Sacro Cuore · ITIRCCS Istituto Auxologico Italiano · ITOspedale Policlinico San Martino · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adrenocorticotropin-secreting pituitary tumor represents about 10 % of pituitary adenomas and at the time of diagnosis most of them are microadenomas. Transsphenoidal surgery is the first-line treatment of Cushing's disease and accurate localization of the tumor within the gland is essential for selectively removing the lesion and preserving normal pituitary function. Magnetic resonance imaging is the best imaging modality for the detection of pituitary tumors, but adrenocorticotropin-secreting pituitary microadenomas are not correctly identified in 30-50 % of cases, because of their size, location, and enhancing characteristics. Several recent studies were performed with the purpose of better localizing the adrenocorticotropin-secreting microadenomas through the use in magnetic resonance imaging of specific sequences, reduced contrast medium dose and high-field technology. Therefore, an improved imaging technique for pituitary disease is mandatory in the suspect of Cushing's disease. The aims of this paper are to present an overview of pituitary magnetic resonance imaging in the diagnosis of Cushing's disease and to provide a magnetic resonance imaging protocol to be followed in case of suspicion adrenocorticotropin-secreting pituitary adenoma.

Indexed as

AdenomaHumansMagnetic Resonance ImagingPituitary ACTH HypersecretionPituitary GlandPituitary NeoplasmsCushing’s diseaseImagingMRIPituitary microadenoma

Identifiers

PMID27435590
OpenAlexW2499546102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.