Evidence map›Paper›PMID 27434771›Full record

ReviewTranscription2016

Ouija board: A transcription factor evolved for only one target in steroid hormone biosynthesis in the fruit fly Drosophila melanogaster.

Yuko S Niwa, Ryusuke Niwa

Abstract readReview
In one paragraph

Review in Transcription, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuko S Niwaa Life Science Center of Tsukuba Advanced Research Alliance, University of Tsukuba , Tsukuba , Ibaraki , Japan.
Ryusuke Niwab Faculty of Life and Environmental Sciences , University of Tsukuba , Tsukuba , Ibaraki , Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors generally regulate gene expression of multiple targets. In contrast, our recent finding suggests that the zinc finger protein Ouija board controls steroid hormone biosynthesis through specific regulation of only one gene spookier in Drosophila. It sheds light on a specialized but essential factor that evolved for one target.

Indexed as

AnimalsBiosynthetic PathwaysCytochrome P-450 Enzyme SystemDrosophila melanogasterDrosophila ProteinsEcdysteroidsGene Expression RegulationInsect HormonesTranscription FactorsCytochrome P-450 Enzyme SystemDrosophila ProteinsEcdysteroidsInsect HormonesOuib protein, Drosophilaspok protein, DrosophilaTranscription FactorsC2H2-type zinc finger proteinDrosophila melanogasterecdysoneecdysteroidOuija boardsteroid hormone biosynthesistranscription

Identifiers

PMID27434771
PMCPMC5066509

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.