Evidence map›Paper›PMID 27434591›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2016

Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins.

David J Marshall, Scott S Harried, John L Murphy, Chad A Hall, Mohammed S Shekhani, Christophe Pain, Conner A Lyons, Antonella Chillemi, Fabio Malavasi, Homer L Pearce and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Drug conjugates-an emerging approach to treat breast cancer.Pharmacology research & perspectives · 2018
    Review
  9. Recent Developments in ADC Technology: Preclinical Studies Signal Future Clinical Trends.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2017
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

David J MarshallCentrose, Madison, Wisconsin, USA.
Scott S HarriedCentrose, Madison, Wisconsin, USA.
John L MurphyCentrose, Madison, Wisconsin, USA.
Chad A HallCentrose, Madison, Wisconsin, USA.
Mohammed S ShekhaniCentrose, Madison, Wisconsin, USA.
Christophe PainCentrose, Madison, Wisconsin, USA.
Conner A LyonsCentrose, Madison, Wisconsin, USA.
Antonella ChillemiLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, Italy.
Fabio MalavasiLaboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Torino, Italy.
Homer L PearceCentrose, Madison, Wisconsin, USA.
Jon S ThorsonCenter for Pharmaceutical Research and Innovation, University of Kentucky College of Pharmacy, Lexington, Kentucky, USA.
James R PrudentCentrose, Madison, Wisconsin, USA.
Centrose (United States) · USUniversity of Turin · ITUniversity of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

The human Na

Indexed as

AnimalsAntibodiesAntineoplastic AgentsCell Line, TumorCell ProliferationCell SurvivalHumansImmunoconjugatesMiceMolecular StructureMolecular Targeted TherapyNeoplasm ProteinsNeoplasmsSmall Molecule LibrariesSodium-Potassium-Exchanging ATPaseXenograft Model Antitumor AssaysAntibodiesAntineoplastic AgentsImmunoconjugatesNeoplasm ProteinsSmall Molecule LibrariesSodium-Potassium-Exchanging ATPase

Identifiers

PMID27434591
PMCPMC5112037
OpenAlexW2482833677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.