ArticleTropical medicine and health2016
Toxoplasma gondii infections among pregnant women, children and HIV-seropositive persons in Accra, Ghana.
Article in Tropical medicine and health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2025Pooled it
- Toxoplasma gondii seroprevalence among pregnant women in Africa: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2024Pooled it
- Toxoplasma gondii seropositivity among patients with sickle cell disease: Prevalence and association with blood transfusion history.PloS one · 2026Article
- Molecular Detection ofPublic health challenges · 2025Article
- Evaluation of Maternal and Neonatal Risk Factors in the Transmission of Toxoplasmosis: A Study on the Detection of Toxoplasma gondii Antibodies in Cord Blood.Ethiopian journal of health sciences · 2025Article
- Co-infections and risk factors of Toxoplasma gondii infection among pregnant women in Ghana: A facility-based cross-sectional study.PloS one · 2025Article
- Seroprevalence and Risk Factors forResearch and reports in tropical medicine · 2025Article
- Article
- In silico study to explore the mechanism of Toxoplasma-induced inflammation and target therapy based on sero and salivary Toxoplasma.Scientific reports · 2024Article
- Article
- Suicide and Inflammation.Advances in experimental medicine and biology · 2023Article
- Assessment of intestinal and blood protozoan infections among pregnant women visiting ante-natal care at Tafo Hospital, Ghana.Heliyon · 2022Article
- Formulation of Neem oil-loaded solid lipid nanoparticles and evaluation of its anti-Toxoplasma activity.BMC complementary medicine and therapies · 2022Article
- Seroprevalence and Risk Factors ofInfectious diseases in obstetrics and gynecology · 2021Article
- Serological survey and risk factors associated withMalawi medical journal : the journal of Medical Association of Malawi · 2020Article
- Review
- Article
- Seroprevalence and risk factors of Toxoplasma gondii among pregnant women in Adwa district, northern Ethiopia.BMC infectious diseases · 2019Article
- Seroprevalence, risk factors and impact ofAAS open research · 2019Article
- Prevalence of Toxoplasma gondii infection in HIV-infected patients and food animals and direct genotyping of T. gondii isolates, Southern Ghana.Parasitology research · 2017Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxoplasma gondii infection can lead to severe disease outcomes in immune-compromised people. This study sought to determine the seroprevalence of anti-T. gondii antibodies among pregnant women, hospitalized children (<5 years old) and HIV-seropositive persons in Accra.
methodsA cross-sectional study was conducted in two hospitals in Accra, and a total of 450 voluntary participants were recruited for the study consisting of 125 pregnant women, 200 children and 125 HIV-seropositive persons. Serum was obtained from venous blood safely drawn from each participant and tested for specific anti-Toxoplasma antibodies IgG and IgM by ELISA. A serological criterion for seropositivity was a positive test result for any of the two anti-Toxoplasma antibodies or a combination of both. Questionnaire interviews were conducted to obtain personal information and Toxoplasma infection risk-related data.
resultsThose who tested seropositive for anti-T. gondii antibodies were 51.2 % (64/125) pregnant women, 58.0 % (116/200) children and 57.6 % (72/125) HIV patients. The major risk factors associated with anti-T. gondii seropositivity were identified as age (in children), handling raw meat and gravida status (in pregnant women). The results of this study confirmed that the seroprevalence of T. gondii infection is high among pregnant women, hospitalized children <5 years old and HIV patients.
conclusionsA further study to investigate pre-pregnancy infections with T. gondii among women of childbearing age, seroconversion rate in pregnant women, rate of mother-to-child transmission and reactivated infections among HIV-seropositive persons is recommended.
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