Evidence map›Paper›PMID 27433132›Full record

ArticleTropical medicine and health2016

Fully immunized child: coverage, timing and sequencing of routine immunization in an urban poor settlement in Nairobi, Kenya.

Martin Kavao Mutua, Elizabeth Kimani-Murage, Nicholas Ngomi, Henrik Ravn, Peter Mwaniki, Elizabeth Echoka

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Tropical medicine and health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04042246 (Knowledge on Vaccination Schedule and Full Immunization, and Its Effect on Vaccine Take-up in Jada Local Government Area in Adamawa State, Northeastern Nigeria), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04042246 nacompletednot on this mapstarted 2019, after this paper: background citation

Knowledge on Vaccination Schedule and Full Immunization, and Its Effect on Vaccine Take-up in Jada Local Government Area in Adamawa State, Northeastern Nigeria

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2019 to 2020Enrolled400ConditionsImmunization, Infection, Educational Problems, Information Seeking BehaviorArmsInformation Provision
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

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  11. Adverse Events Following Immunizations in Infants Under 1 Year of Age in Lorestan Province, Western Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Martin Kavao MutuaAfrican Population and Health Research Center, Manga Close, Nairobi, Kenya ; Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Elizabeth Kimani-MurageAfrican Population and Health Research Center, Manga Close, Nairobi, Kenya ; International Health Institute, Brown University, Providence, RI USA.
Nicholas NgomiAfrican Population and Health Research Center, Manga Close, Nairobi, Kenya.
Henrik RavnResearch Center for Vitamins and Vaccines, 5 Artillerivej, Copenhagen, Denmark ; Bandim Health Project, Statens Serum Institut, 5 Artillerivej, Copenhagen, Denmark ; OPEN, University of Southern Denmark/Odense University Hospital, Odense, Denmark.
Peter MwanikiJomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Elizabeth EchokaAfrican Population and Health Research Center, Manga Close, Nairobi, Kenya ; Centre for Public Health Research, Kenya Medical Research Institute, Nairobi, Kenya.
African Population and Health Research Center · KEJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KE

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundMore efforts have been put in place to increase full immunization coverage rates in the last decade. Little is known about the levels and consequences of delaying or vaccinating children in different schedules. Vaccine effectiveness depends on the timing of its administration, and it is not optimal if given early, delayed or not given as recommended. Evidence of non-specific effects of vaccines is well documented and could be linked to timing and sequencing of immunization. This paper documents the levels of coverage, timing and sequencing of routine childhood vaccines.

methodsThe study was conducted between 2007 and 2014 in two informal urban settlements in Nairobi. A total of 3856 children, aged 12-23 months and having a vaccination card seen were included in analysis. Vaccination dates recorded from the cards seen were used to define full immunization coverage, timeliness and sequencing. Proportions, medians and Kaplan-Meier curves were used to assess and describe the levels of full immunization coverage, vaccination delays and sequencing.

resultsThe findings indicate that 67 % of the children were fully immunized by 12 months of age. Missing measles and third doses of polio and pentavalent vaccine were the main reason for not being fully immunized. Delays were highest for third doses of polio and pentavalent and measles. About 22 % of fully immunized children had vaccines in an out-of-sequence manner with 18 % not receiving pentavalent together with polio vaccine as recommended.

conclusionsResults show higher levels of missed opportunities and low coverage of routine childhood vaccinations given at later ages. New strategies are needed to enable health care providers and parents/guardians to work together to increase the levels of completion of all required vaccinations. In particular, more focus is needed on vaccines given in multiple doses (polio, pentavalent and pneumococcal conjugate vaccines).

Indexed as

CoverageFully immunized childVaccination delayVaccination sequence

Identifiers

PMID27433132
PMCPMC4940963
OpenAlexW2415548117

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.