ArticleProceedings of the National Academy of Sciences of the United States of America2016
Effects of the population pedigree on genetic signatures of historical demographic events.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Understanding admixture fractions: theory and estimation of gene-flow.Journal of mathematical biology · 2024Article
- On the number of genealogical ancestors tracing to the source groups of an admixed population.Genetics · 2023Article
- Pedigree in the biparental Moran model.Journal of mathematical biology · 2022Article
- Pseudoreplication in genomic-scale data sets.Molecular ecology resources · 2022Article
- Variance and limiting distribution of coalescence times in a diploid model of a consanguineous population.Theoretical population biology · 2021Article
- Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data.PLoS genetics · 2020Article
- Joint Estimation of Pedigrees and Effective Population Size Using Markov Chain Monte Carlo.Genetics · 2019Article
- Article
- Incorporating non-equilibrium dynamics into demographic history inferences of a migratory marine species.Heredity · 2019Article
- Composite likelihood method for inferring local pedigrees.PLoS genetics · 2017Article
- In the light of evolution X: Comparative phylogeography.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
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Authors and funding
3 authors.
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Abstract
Genetic variation among loci in the genomes of diploid biparental organisms is the result of mutation and genetic transmission through the genealogy, or population pedigree, of the species. We explore the consequences of this for patterns of variation at unlinked loci for two kinds of demographic events: the occurrence of a very large family or a strong selective sweep that occurred in the recent past. The results indicate that only rather extreme versions of such events can be expected to structure population pedigrees in such a way that unlinked loci will show deviations from the standard predictions of population genetics, which average over population pedigrees. The results also suggest that large samples of individuals and loci increase the chance of picking up signatures of these events, and that very large families may have a unique signature in terms of sample distributions of mutant alleles.
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