ArticleJournal of neural engineering2016
Altered motor unit discharge patterns in paretic muscles of stroke survivors assessed using surface electromyography.
Article in Journal of neural engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Structural and pathophysiological muscle changes up to one year after post-stroke hemiplegia: a systematic review.European journal of physical and rehabilitation medicine · 2023Pooled it
- Disrupted bilateral co-ordination of soleus motor units during early subacute stroke rehabilitation.The Journal of physiology · 2026Article
- Stroke increases motor output variability during maximal voluntary isometric contractions of knee extensor muscles in adults.Physiological reports · 2026Article
- Leveraging neural drive to assess hand motor function in individuals with chronic stroke.Journal of neuroengineering and rehabilitation · 2026Article
- An Intuitive, Bidirectional, and Adaptive Functional Electrical Stimulation System for Hand Rehabilitation.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- In vivo estimation of motor unit intrinsic properties in individuals with spinal cord injury.Journal of neuroengineering and rehabilitation · 2025Article
- Individualized muscle architecture and contractile properties of ankle plantarflexors and dorsiflexors in post-stroke individuals.Frontiers in bioengineering and biotechnology · 2024Article
- Objectivizing Measures of Post-Stroke Hand Rehabilitation through Multi-Disciplinary Scales.Journal of clinical medicine · 2023Review
- Compound muscle action potential (CMAP) scan examination of paretic and contralateral muscles reveals motor unit alterations after stroke.Science China. Life sciences · 2023Article
- Arthrogenic muscle inhibition after anterior cruciate ligament injury: Injured and uninjured limb recovery over time.Frontiers in sports and active living · 2023Article
- Article
- Teaching Essential EMG Theory to Kinesiologists and Physical Therapists Using Analogies Visual Descriptions, and Qualitative Analysis of Biophysical Concepts.Sensors (Basel, Switzerland) · 2022Article
- Motor unit distribution and recruitment in spastic and non-spastic bilateral biceps brachii muscles of chronic stroke survivors.Journal of neural engineering · 2022Article
- Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2022Article
- Neuromotor control associates with muscle weakness observed with McArdle sign of multiple sclerosis.Annals of clinical and translational neurology · 2022Article
- Article
- Muscle Fiber Diameter and Density Alterations after Stroke Examined by Single-Fiber EMG.Neural plasticity · 2021Article
- Malondialdehyde as a Useful Biomarker of Low Hand Grip Strength in Community-Dwelling Stroke Patients.International journal of environmental research and public health · 2020Article
- Effects of Changes in Ankle Joint Angle on the Relation Between Plantarflexion Torque and EMG Magnitude in Major Plantar Flexors of Male Chronic Stroke Survivors.Frontiers in neurology · 2020Article
- Single channel surface electromyogram deconvolution to explore motor unit discharges.Medical & biological engineering & computing · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveHemispheric stroke survivors often show impairments in voluntary muscle activation. One potential source of these impairments could come from altered control of muscle, via disrupted motor unit (MU) firing patterns. In this study, we sought to determine whether MU firing patterns are modified on the affected side of stroke survivors, as compared with the analogous contralateral muscle. APPROACH: Using a novel surface electromyogram (EMG) sensor array, coupled with advanced template recognition software (dEMG) we recorded surface EMG signals over the first dorsal interosseous (FDI) muscle on both paretic and contralateral sides. Recordings were made as stroke survivors produced isometric index finger abductions over a large force range (20%-60% of maximum). Utilizing the dEMG algorithm, MU firing rates, recruitment thresholds, and action potential amplitudes were estimated for concurrently active MUs in each trial. MAIN
resultsOur results reveal significant changes in the firing rate patterns in paretic FDI muscle, in that the discharge rates, characterized in relation to recruitment force threshold and to MU size, were less clearly correlated with recruitment force than in contralateral FDI muscles. Firing rates in the affected muscle also did not modulate systematically with the level of voluntary muscle contraction, as would be expected in intact muscles. These disturbances in firing properties also correlated closely with the impairment of muscle force generation. SIGNIFICANCE: Our results provide strong evidence of disruptions in MU firing behavior in paretic muscles after a hemispheric stroke, suggesting that modified control of the spinal motoneuron pool could be a contributing factor to muscular weakness in stroke survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.