Evidence map›Paper›PMID 27432441›Full record

Trial reportInternational journal of behavioral medicine2017

Cognitive-Behavioural Therapy for Inflammatory Bowel Disease: 24-Month Data from a Randomised Controlled Trial.

Antonina Mikocka-Walus, Peter Bampton, David Hetzel, Patrick Hughes, Adrian Esterman, Jane M Andrews

Registry-linked trialOpen access · hybridAbstract readComparative StudyRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of behavioral medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03667586 (The Impact of Group Cognitive Behavioral Psychotherapy on Disease Severity and Psychosocial Functioning of Inflammatory Bowel Disease Patients), which is not on this map. Cited by 44 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 7 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03667586 nacompletednot on this mapstarted 2019, after this paper: background citation

The Impact of Group Cognitive Behavioral Psychotherapy on Disease Severity and Psychosocial Functioning of Inflammatory Bowel Disease Patients

TypeinterventionalSponsorUniversity Hospital of PatrasRan2019 to 2022Enrolled79ConditionsInflammatory Bowel DiseasesArmsGroup cognitive behavioral therapy
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 7 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025
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  10. The specialized educational and psychological counseling in inflammatory bowel disease patients - a target or a challenge?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Antonina Mikocka-WalusSchool of Nursing and Midwifery and Sansom Institute for Health Research, University of South Australia, Adelaide, 5001, Australia. Antonina.mikocka-walus@york.ac.uk.ORCID 0000-0003-4864-3956
Peter BamptonSchool of Medicine, Flinders University, Bedford Park, 5042, Australia.
David HetzelDepartment of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, 5001, Australia.
Patrick HughesCentre for Nutrition and Gastrointestinal Diseases, School of Medicine, University of Adelaide, Adelaide, 5001, Australia.
Adrian EstermanSchool of Nursing and Midwifery and Sansom Institute for Health Research, University of South Australia, Adelaide, 5001, Australia.
Jane M AndrewsSchool of Medicine, Flinders University, Bedford Park, 5042, Australia.
Royal Adelaide Hospital · AUUniversity of South Australia · AUFlinders University · AUThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is ongoing controversy on the effectiveness of psychotherapy in inflammatory bowel disease (IBD). In the few small studies, cognitive-behavioural therapy (CBT) has been shown to alleviate symptoms of anxiety or depression. However, there is little research on the impact of CBT on physical outcomes in IBD and no studies on long-term effectiveness of CBT.

methodsThe present two-arm pragmatic randomised controlled trial aimed to establish the impact of CBT on disease course after 24 months of observation. The study compared standard care plus CBT (+CBT) with standard care alone (SC). CBT was delivered over 10 weeks, face-to-face (F2F) or online (cCBT). The data were analysed using linear mixed-effects models.

resultsCBT did not significantly influence disease activity as measured by disease activity indices at 24 months (Crohn's Disease Activity Index (CDAI), p = 0.92; Simple Clinical Colitis Activity Index (SCCAI), p = 0.88) or blood parameters (C-reactive protein (CRP), p < 0.62; haemoglobin (Hb), p = 0.77; platelet, p = 0.64; white cell count (WCC), p = 0.59) nor did CBT significantly affect mental health, coping or quality of life (all p > 0.05).

conclusionsTherefore, we conclude that CBT does not influence the course of IBD over 24 months. Given the high rate of attrition, particularly in the CBT group, future trials should consider a personalised approach to psychotherapy, perhaps combining online and one-to-one therapist time.

Indexed as

AnxietyCognitive Behavioral TherapyDepressionFollow-Up StudiesHumansInflammatory Bowel DiseasesMental HealthPsychotherapyQuality of LifeCognitive-behavioural therapyDisease courseInflammatory bowel disease

Identifiers

PMID27432441
PMCPMC5288424
OpenAlexW2500504100

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.