ArticleAlcohol (Fayetteville, N.Y.)2017
Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.
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Article in Alcohol (Fayetteville, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
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Who cites it
31 citing papers in PubMed, 45 citations in OpenAlex.
- Epigenetic Landscapes of Methamphetamine Addiction: Unravelling the Diagnostic Potential of Gene Methylation.Addiction biology · 2025Article
- Pharmacological Actions of Potassium Channel Openers on Voltage-Gated Potassium Channels.Pharmaceuticals (Basel, Switzerland) · 2025Article
- KAlcohol (Fayetteville, N.Y.) · 2025Article
- Decreased voluntary alcohol intake and ventral striatal epigenetic and transcriptional remodeling in male Acss2 KO mice.Neuropharmacology · 2025Article
- Escalated oxycodone self-administration is associated with expression of voltage gated and calcium activated potassium channels in the mesocorticolimbic system in rats.Frontiers in pharmacology · 2025Article
- Chronic alcohol consumption alters sex-dependent BNST neuron function in rhesus macaques.Neurobiology of stress · 2024Article
- Synaptic Mechanisms of Ethanol Tolerance and Neuroplasticity: Insights from Invertebrate Models.International journal of molecular sciences · 2024Review
- Chronic alcohol consumption alters sex-dependent BNST neuron function in rhesus macaques.bioRxiv : the preprint server for biology · 2024Article
- Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking.Translational psychiatry · 2023Article
- Adaptor protein complex 2 in the orbitofrontal cortex predicts alcohol use disorder.Molecular psychiatry · 2023Article
- Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons.Neuropharmacology · 2023Article
- Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons.bioRxiv : the preprint server for biology · 2023Article
- Modulation of neuronal excitability by binge alcohol drinking.Frontiers in molecular neuroscience · 2023Review
- Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022Review
- The histone methyltransferase G9a mediates stress-regulated alcohol drinking.Addiction biology · 2022Article
- Potassium Channels and Their Potential Roles in Substance Use Disorders.International journal of molecular sciences · 2021Review
- Physiology and Therapeutic Potential of SK, H, and M Medium AfterHyperPolarization Ion Channels.Frontiers in molecular neuroscience · 2021Review
- Bioinformatics identification and pharmacological validation of Kcnn3/KTranslational psychiatry · 2020Article
- Absence of effects of intermittent access to alcohol on negative affective and anxiety-like behaviors in male and female C57BL/6J mice.Alcohol (Fayetteville, N.Y.) · 2020Article
- A Single Prior Injection of Methamphetamine Enhances Methamphetamine Self-Administration (SA) and Blocks SA-Induced Changes in DNA Methylation and mRNA Expression of Potassium Channels in the Rat Nucleus Accumbens.Molecular neurobiology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Jennifer A RinkerDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA.
Diana B FulmerDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA.
Heather Trantham-DavidsonDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA.
Maren L SmithDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Robert W WilliamsDepartment of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Marcelo F LopezDepartment of Psychiatry & Behavioral Sciences, Charleston Alcohol Research Center, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC 29425, USA.
Patrick K RandallDepartment of Psychiatry & Behavioral Sciences, Charleston Alcohol Research Center, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC 29425, USA.
L Judson ChandlerDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA.
Michael F MilesDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA 23298, USA.
Howard C BeckerDepartment of Psychiatry & Behavioral Sciences, Charleston Alcohol Research Center, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC 29425, USA; Ralph H. Johnson VA Medical Center, Charleston, SC 29425, USA.
Patrick J MulhollandDepartment of Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA; Department of Psychiatry & Behavioral Sciences, Charleston Alcohol Research Center, Addiction Sciences Division, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: mulholl@musc.edu.
Medical University of South Carolina · USVirginia Commonwealth University · USUniversity of Tennessee Health Science Center · US
Funding
TREATING ETHANOL WITHDRAWAL WITH LORAZEPAM/NALTREXONEP50AA010761 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI John J. Woodward · 1996 to 2026
$46.8MProject 5 - Genetic architecture of alcohol use disorder using cross-trait genetic correlations and public next-generation sequencing studiesP50AA022537 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Brien P Riley · 2014 to 2026
$19.6MEthanol Dependence &Stress Effects on Ethanol DrinkingU01AA014095 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOWARD C. BECKER · 2003 to 2026
$9.0MKv7 channels and heavy alcohol drinkingR01AA023288 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MULHOLLAND, PATRICK J. · 2014 to 2023
$3.4MINIA-STRESS: Informatics and Analysis CoreU01AA016662 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILLIAMS, ROBERT W. · 2007 to 2016
$2.9MStress and Ethanol Dependence: SK Channels and GlutamateU01AA020930 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MULHOLLAND, PATRICK J. · 2012 to 2021
$2.6MOf Mice and Primates: Gene Networks in Excessive Ethanol Consumption and AnxietyU01AA016667 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MILES, MICHAEL F · 2007 to 2016
$2.4MChronic Intermittent Ethanol and Kv4.2 ChannelsR01AA022701 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI CHANDLER, L JUDSON · 2015 to 2019
$1.7MMouse Chronic Intermittent Ethanol (CIE) CoreU01AA020929 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LOPEZ, MARCELO F. · 2012 to 2015
$1.5MMouse Chronic Intermittent Ethanol (CIE) CoreU24AA020929 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LOPEZ, MARCELO F. · 2016 to 2021
$1.1MDependence-Induced Excessive Ethanol Consumption: Role of Corticostriatal Kv7 ChannelsK01AA025110 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RINKER, JENNIFER ANNE · 2017 to 2021
$930kEffects of Adolescent Alcohol Exposure on Decision Making in Adult RatsK01AA022475 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI TRANTHAM-DAVIDSON, HEATHER L · 2014 to 2017
$681kNIAAA NIH HHS K01 AA022475NIAAA NIH HHS K01 AA025110NIAAA NIH HHS P50 AA010761NIAAA NIH HHS P50 AA022537NIAAA NIH HHS R01 AA022701NIAAA NIH HHS R01 AA023288NIAAA NIH HHS U01 AA014095NIAAA NIH HHS U01 AA016662NIAAA NIH HHS U01 AA016667NIAAA NIH HHS U01 AA020929NIAAA NIH HHS U01 AA020930NIAAA NIH HHS U24 AA020929
Abstract
Alcohol (ethanol) dependence is a chronic relapsing brain disorder partially influenced by genetics and characterized by an inability to regulate harmful levels of drinking. Emerging evidence has linked genes that encode K
Indexed as
Alcohol DrinkingAnimalsCarbamatesFemaleGene Expression RegulationMaleMembrane Transport ModulatorsMiceMice, Inbred C57BLMice, Inbred DBAPharmacogeneticsPhenylenediaminesPotassium ChannelsCarbamatesezogabineMembrane Transport ModulatorsPhenylenediaminesPotassium ChannelsAlcohol use disorderBXD miceK(+) channelsNucleus accumbensPharmacogeneticsPrefrontal cortex
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.