Evidence map›Paper›PMID 27432121›Full record

ArticleThe Journal of infectious diseases2016

Reticulocyte Preference and Stage Development of Plasmodium vivax Isolates.

Caeul Lim, Ligia Pereira, Kathryn Shaw Saliba, Anjali Mascarenhas, Jennifer N Maki, Laura Chery, Edwin Gomes, Pradipsinh K Rathod, Manoj T Duraisingh

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Overview ofComparative medicine · 2024
    Review
  5. Complement receptor 1 is the human erythrocyte receptor forProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Contrasting epidemiology and genetic variation of Plasmodium vivax infecting Duffy-negative individuals across Africa.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  16. Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions.International journal for parasitology. Drugs and drug resistance · 2021
    Review
  17. Article
  18. Article
  19. Home Sweet Home:Frontiers in cellular and infection microbiology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caeul LimDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
Ligia PereiraDepartment of Chemistry, University of Washington, Seattle Department of Medicine, Goa Medical College and Hospital, Bambolim, India.
Kathryn Shaw SalibaDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
Anjali MascarenhasDepartment of Chemistry, University of Washington, Seattle Department of Medicine, Goa Medical College and Hospital, Bambolim, India.
Jennifer N MakiDepartment of Chemistry, University of Washington, Seattle.
Laura CheryDepartment of Chemistry, University of Washington, Seattle.
Edwin GomesDepartment of Medicine, Goa Medical College and Hospital, Bambolim, India.
Pradipsinh K RathodDepartment of Chemistry, University of Washington, Seattle.
Manoj T DuraisinghDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

Funding

Shared TechnologyU19AI089688 · NIAID · UNIVERSITY OF WASHINGTON · PI TULJAPURKAR, SHRIPAD D. · 2010 to 2023
$22.4M
NIAID NIH HHS U19 AI089688
6 · The paper itself

Abstract

Plasmodium vivax, the most widely distributed human malaria parasite, is restricted to reticulocytes, limiting its asexual proliferation. In recent years, cases of severe and high-level P. vivax parasitemia have been reported, challenging the assumption that all isolates are equally restricted. In this article, we analyze the reticulocyte preference of a large number of Indian P. vivax isolates. Our results show that P. vivax isolates significantly vary in their level of reticulocyte preference. In addition, by carefully staging the parasites, we find that P. vivax schizonts are largely missing in peripheral blood, with the presence of schizonts in circulation correlating with a high reticulocyte preference.

Indexed as

Viral TropismHumansMalaria, VivaxPlasmodium vivaxReticulocytesasexual stagePlasmodium vivaxreticulocyte preference

Identifiers

PMID27432121
PMCPMC5021230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.