ArticleJournal of the American Society for Mass Spectrometry2016
2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach.
Article in Journal of the American Society for Mass Spectrometry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Absorption Mode Broadband 2D MS for Proteomics and Metabolomics.Journal of the American Society for Mass Spectrometry · 2026Article
- Chromatography-Free Analysis of Mixtures Using a Two-Dimensional Mass Spectrometry (2DMS)-Enabled Quadrupole Time-of-Flight (QToF) Analyzer.Analytical chemistry · 2026Article
- A Conformation-Specific Approach to Native Top-down Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2024Article
- Advancing PROTAC Characterization: Structural Insights through Adducts and Multimodal Tandem-MS Strategies.Journal of the American Society for Mass Spectrometry · 2024Article
- Top-Down Proteoform Analysis by 2D MS with Quadrupolar Detection.Analytical chemistry · 2023Article
- Ultra-Accurate Correlation between Precursor and Fragment Ions in Two-Dimensional Mass Spectrometry: Acetylated vs Trimethylated Histone Peptides.Journal of the American Society for Mass Spectrometry · 2023Article
- 193 nm Ultraviolet Photodissociation for the Characterization of Singly Charged Proteoforms Generated by MALDI.Journal of the American Society for Mass Spectrometry · 2023Article
- Phase Correction for Absorption Mode Two-Dimensional Mass Spectrometry.Molecules (Basel, Switzerland) · 2021Article
- Masked Multiplexed Separations to Enhance Duty Cycle for Structures for Lossless Ion Manipulations.Analytical chemistry · 2021Article
- Narrowband Modulation Two-Dimensional Mass Spectrometry and Label-Free Relative Quantification of Histone Peptides.Analytical chemistry · 2020Article
- Ion Activation Methods for Peptides and Proteins.Analytical chemistry · 2020Review
- Phase relationships in two-dimensional mass spectrometry.Journal of the American Society for Mass Spectrometry · 2019Article
- Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry.European biophysics journal : EBJ · 2019Review
- Application of Tandem Two-Dimensional Mass Spectrometry for Top-Down Deep Sequencing of Calmodulin.Journal of the American Society for Mass Spectrometry · 2018Article
- Bottom-Up Two-Dimensional Electron-Capture Dissociation Mass Spectrometry of Calmodulin.Journal of the American Society for Mass Spectrometry · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FT-ICR MS) allows data-independent fragmentation of all ions in a sample and correlation of fragment ions to their precursors through the modulation of precursor ion cyclotron radii prior to fragmentation. Previous results show that implementation of 2D FT-ICR MS with infrared multi-photon dissociation (IRMPD) and electron capture dissociation (ECD) has turned this method into a useful analytical tool. In this work, IRMPD tandem mass spectrometry of calmodulin (CaM) has been performed both in one-dimensional and two-dimensional FT-ICR MS using a top-down and bottom-up approach. 2D IRMPD FT-ICR MS is used to achieve extensive inter-residue bond cleavage and assignment for CaM, using its unique features for fragment identification in a less time- and sample-consuming experiment than doing the same thing using sequential MS/MS experiments. Graphical Abstract ᅟ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.