Evidence map›Paper›PMID 27431491›Full record

ArticleBMC research notes2016

Secondary consent to biospecimen use in a prostate cancer biorepository.

Bettina F Drake, Katherine Brown, Lucy D'Agostino McGowan, Jennifer Haslag-Minoff, Kimberly Kaphingst

Abstract read
In one paragraph

Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Trust and Support for Cancer Research Biobanks: Insights from Cancer Patients in Poland.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Human gene therapy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bettina F DrakeDivision of Public Health Sciences, Washington University School of Medicine, 600 S. Taylor Ave, Campus Box 8100, St. Louis, MO, 63110, USA. drakeb@wustl.edu.ORCID http://orcid.org/0000-0001-9340-5848
Katherine BrownDivision of Public Health Sciences, Washington University School of Medicine, 600 S. Taylor Ave, Campus Box 8100, St. Louis, MO, 63110, USA.
Lucy D'Agostino McGowanVanderbilt University, Nashville, TN, USA.
Jennifer Haslag-MinoffUniversity of Missouri School of Medicine, Columbia, MO, USA.
Kimberly KaphingstDepartment of Communication, University of Utah, Salt Lake City, UT, USA.

Funding

Training ProgramU54CA153460 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2010 to 2015
$5.3M
NCI NIH HHS U54 CA153460
6 · The paper itself

Abstract

backgroundBiorepository research has substantial societal benefits. This is one of the few studies to focus on male willingness to allow future research use of biospecimens.

methodsThis study analyzed the future research consent questions from a prostate cancer biorepository study (N = 1931). The consent form asked two questions regarding use of samples in future studies (1) without and (2) with protected health information (PHI). Yes to both questions of use of samples was categorized as Yes-Always; Yes to without and No to with PHI was categorized as Yes-Conditional; No to without PHI was categorized as Never. We analyzed this outcome to determine significant predictors for consent to Yes-Always vs. Yes-Conditional.

results99.33 % consented to future use of samples; 88.19 % consented to future use without PHI, and among those men 10.2 % consented to future use with PHI. Comparing Yes Always and Yes Conditional responses, bivariate analyses showed that race, family history, stage of cancer, and grade of cancer (Gleason), were significant at the α = 0.05 level. Using stepwise multivariable logistic regression, we found that African-American men were significantly more likely to respond Yes Always when compared to White men (p < 0.001). Those with a family history of prostate cancer were significantly more likely to respond Yes Always (p = 0.002).

conclusionsThere is general willingness to consent to future use of specimens without PHI among men.

Indexed as

AgedBlack or African AmericanBlack PeopleHealth Information ExchangeHealth Records, PersonalHumansInformed ConsentLogistic ModelsMaleMiddle AgedNeoplasm GradingNeoplasm StagingProstateProstatic NeoplasmsSurveys and QuestionnairesTissue BanksAfrican–AmericanBiorepositoryConsentProstate cancerProtected health information

Identifiers

PMID27431491
PMCPMC4949745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.