ReviewRheumatic diseases clinics of North America2016
The Proteomics of Saliva in Sjögren's Syndrome.
Review in Rheumatic diseases clinics of North America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Sjögren's syndrome: novel insights from proteomics and miRNA expression analysis.Frontiers in immunology · 2023Pooled it
- Saliva Proteomics as Fluid Signature of Inflammatory and Immune-Mediated Skin Diseases.International journal of molecular sciences · 2021Pooled it
- Salivary Dysfunction in Primary and Secondary Sjögren's Syndrome: Functional Assessment and the Exploratory Role of Salivary Microcrystallization.Dentistry journal · 2026Article
- Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren's syndrome.International journal of oral science · 2025Article
- The utility of microbiome (microbiota) and exosomes in dentistry.Journal of dental sciences · 2024Review
- Therapeutic potential of exosomes derived from mesenchymal stem cells for treatment of systemic lupus erythematosus.Journal of inflammation (London, England) · 2024Review
- Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023Review
- The Potential Utility of Salivary and Tear Proteomics to Discriminate Sjögren's Disease from Non-Sjögren's Sicca.International journal of molecular sciences · 2023Review
- Expression of ICOS in the salivary glands of patients with primary Sjogren's syndrome and its molecular mechanism.Molecular medicine reports · 2022Article
- Article
- Salivary Glycopatterns as Potential Non-Invasive Biomarkers for Diagnosing and Reflecting Severity and Prognosis of Diabetic Nephropathy.Frontiers in endocrinology · 2022Article
- Proteomic characteristics of saliva in patients with different subgroups of IgG4-RD.Frontiers in immunology · 2022Article
- A distinguishing profile of chemokines, cytokines and biomarkers in the saliva of children with Sjögren's syndrome.Rheumatology (Oxford, England) · 2021Article
- Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva.Journal of dental research · 2021Review
- Saliva, a bodily fluid with recognized and potential diagnostic applications.Journal of separation science · 2021Review
- Analysis of Multimerin 1 (MMRN1) expression in ovarian cancer.Molecular biology reports · 2020Article
- Proteomics-based analysis indicating α-enolase as a potential biomarker in primary Sjögren's syndrome.Gland surgery · 2020Article
- Integrated glycomics strategy for the evaluation of glycosylation alterations in salivary proteins associated with type 2 diabetes mellitus.RSC advances · 2020Article
- The Challenges of OSCC Diagnosis: Salivary Cytokines as Potential Biomarkers.Journal of clinical medicine · 2020Review
- Defining Parallels between the Salivary Glands and Pancreas to Better Understand Pancreatic Carcinogenesis.Biomedicines · 2020Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
One of the main characteristics of primary Sjögren's syndrome (pSS) is chronic dysfunction and destruction of the salivary and lacrimal glands; their secretory biofluids should reflect the glandular biological status. Saliva is a heterogeneous biofluid comprised of biomolecules and omics constituents that are altered in response to various diseases. Scientific effort has evaluated saliva proteome to diagnose, monitor, and prognosticate pSS. This article reviews the recent advances in salivary proteomics in the context of pSS, highlighting the most significant and promising findings. Determining saliva as a credible means of early disease detection could lead to translational advantages and significant clinical opportunities for pSS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.