ArticleMolecular psychiatry2016
Differential sensitivity to the environment: contribution of cognitive biases and genes to psychological wellbeing.
Article in Molecular psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review of Polygenic Gene-Environment Interaction in Tobacco, Alcohol, and Cannabis Use.Behavior genetics · 2019Pooled it
- Genetic Differences in Reactivity to the Environment Impact Psychotic-Like and Affective Reactivity in Daily Life.Schizophrenia bulletin · 2025Article
- Factors Associated with the Development of Depression and the Influence of Obesity on Depressive Disorders: A Narrative Review.Biomedicines · 2024Review
- Good parent-child relationship protects against alcohol use in maltreated adolescent females carrying theFrontiers in psychiatry · 2024Article
- Association of polygenic scores for depression and neuroticism with perceived stress in daily life during a long-lasting stress period.Genes, brain, and behavior · 2023Article
- Social network size and personality traits independently and prospectively predict distress disorders and suicidal behavior in U.S. Army soldiers.Psychological medicine · 2023Article
- Transcriptional profiles in the mouse amygdala after a cognitive judgment bias test largely depend on the genotype.Frontiers in molecular neuroscience · 2022Article
- A neural model of vulnerability and resilience to stress-related disorders linked to differential susceptibility.Molecular psychiatry · 2022Review
- Does urbanicity modify the relationship between a polygenic risk score for depression and mental health symptoms? Cross-sectional evidence from the observational HUNT Study in Norway.Journal of epidemiology and community health · 2021Observational
- The Architecture of Cognitive Vulnerability to Depressive Symptoms in Adolescence: A Longitudinal Network Analysis Study.Research on child and adolescent psychopathology · 2021Article
- Prenatal Glucocorticoid-Exposed Infants Do Not Show an Age-Typical Fear Bias at 8 Months of Age - Preliminary Findings From the FinnBrain Birth Cohort Study.Frontiers in psychology · 2021Article
- Anxiety and Depressive Symptom Trajectories in Adolescence and the Co-Occurring Development of Cognitive Biases: Evidence from the CogBIAS Longitudinal Study.Journal of abnormal child psychology · 2020Article
- Article
- Polygenic liability for schizophrenia and childhood adversity influences daily-life emotion dysregulation and psychosis proneness.Acta psychiatrica Scandinavica · 2020Article
- After the Honeymoon: Neural and Genetic Correlates of Romantic Love in Newlywed Marriages.Frontiers in psychology · 2020Article
- The CogBIAS longitudinal study of adolescence: cohort profile and stability and change in measures across three waves.BMC psychology · 2019Article
- Paradoxical effects of exercise on hippocampal plasticity and cognition in mice with a heterozygous null mutation in the serotonin transporter gene.British journal of pharmacology · 2019Article
- Threat-related disorders as persistent motivational states of defense.Current opinion in behavioral sciences · 2019Article
- Polygenic differential susceptibility to cumulative stress exposure and childhood obesity.International journal of obesity (2005) · 2018Article
- The CogBIAS longitudinal study protocol: cognitive and genetic factors influencing psychological functioning in adolescence.BMC psychology · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Negative cognitive biases and genetic variation have been associated with risk of psychopathology in largely independent lines of research. Here, we discuss ways in which these dynamic fields of research might be fruitfully combined. We propose that gene by environment (G × E) interactions may be mediated by selective cognitive biases and that certain forms of genetic 'reactivity' or 'sensitivity' may represent heightened sensitivity to the learning environment in a 'for better and for worse' manner. To progress knowledge in this field, we recommend including assessments of cognitive processing biases; examining G × E interactions in 'both' negative and positive environments; experimentally manipulating the environment when possible; and moving beyond single-gene effects to assess polygenic sensitivity scores. We formulate a new methodological framework encapsulating cognitive and genetic factors in the development of both psychopathology and optimal wellbeing that holds long-term promise for the development of new personalized therapies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.