Evidence map›Paper›PMID 27430544›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Key Knowledge Gaps for Plasmodium vivax Control and Elimination.

Quique Bassat, Mar Velarde, Ivo Mueller, Jessica Lin, Toby Leslie, Chansuda Wongsrichanalai, J Kevin Baird

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Population heterogeneity in Plasmodium vivax relapse risk.PLoS neglected tropical diseases · 2022
    Trial
  3. Article
  4. Article
  5. Article
  6. Mediterranean journal of hematology and infectious diseases · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Update and elucidation ofComputational and structural biotechnology journal · 2022
    Article
  14. Article
  15. Article
  16. Spatial and Temporal Patterns of Malaria in Phu Yen Province, Vietnam, from 2005 to 2016.The American journal of tropical medicine and hygiene · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Quique BassatISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Mar VelardeISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Ivo MuellerPopulation Health and Immunology Division, Walter and Eliza Hall Institute, Victoria, Australia.
Jessica LinDivision of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina.
Toby LeslieHealth Protection and Research Organisation, Kabul, Afghanistan.
Chansuda WongsrichanalaiIndependent Scholar, Bangkok, Thailand.
J Kevin BairdCentre for Tropical Medicine, University of Oxford, Oxford, United Kingdom.

Funding

Genetic determinants of Plasmodium vivax relapseK08AI110651 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, JESSICA · 2014 to 2018
$869k
NIAID NIH HHS K08 AI110651Wellcome Trust
6 · The paper itself

Abstract

There is inadequate understanding of the biology, pathology, transmission, and control of Plasmodium vivax, the geographically most widespread cause of human malaria. During the last decades, study of this species was neglected, in part due to the erroneous belief that it is intrinsically benign. In addition, many technical challenges in culturing the parasite also hampered understanding its fundamental biology and molecular and cellular responses to chemotherapeutics. Research on vivax malaria needs to be substantially expanded over the next decade to accelerate its elimination and eradication. This article summarizes key knowledge gaps identified by researchers, national malaria control programs, and other stakeholders assembled by the World Health Organization to develop strategies for controlling and eliminating vivax malaria. The priorities presented in this article emerged in these technical discussions, and were adopted by expert consensus of the authors. All involved understood the priority placed upon pragmatism in this research agenda, that is, focus upon tools delivering better prevention, diagnosis, treatment, and surveillance of P. vivax.

Indexed as

Plasmodium vivaxAnimalsCulicidaeCytochrome P-450 CYP2D6Global HealthGlucosephosphate Dehydrogenase DeficiencyHumansInsect VectorsMalaria, VivaxPopulation SurveillanceWorld Health OrganizationCytochrome P-450 CYP2D6

Identifiers

PMID27430544
PMCPMC5201224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.