Evidence map›Paper›PMID 27430512›Full record

ArticleWorld journal of microbiology & biotechnology2016

Genetic dissection of acetic acid tolerance in Saccharomyces cerevisiae.

Peng Geng, Yin Xiao, Yun Hu, Haiye Sun, Wei Xue, Liang Zhang, Gui-Yang Shi

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Adaptive Response and Tolerance to Acetic Acid inFrontiers in microbiology · 2018
    Review
  4. Rapid Identification of Major QTLFrontiers in microbiology · 2018
    Article
  5. Omics analysis of acetic acid tolerance in Saccharomyces cerevisiae.World journal of microbiology & biotechnology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peng GengNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Yin XiaoNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Yun HuThe Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, China.
Haiye SunNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Wei XueSchool of Information Science and Technology, Nanjing Agricultural University, Nanjing, China.
Liang ZhangNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China. zhangl@jiangnan.edu.cn.
Gui-Yang ShiNational Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dissection of the hereditary architecture underlying Saccharomyces cerevisiae tolerance to acetic acid is essential for ethanol fermentation. In this work, a genomics approach was used to dissect hereditary variations in acetic acid tolerance between two phenotypically different strains. A total of 160 segregants derived from these two strains were obtained. Phenotypic analysis indicated that the acetic acid tolerance displayed a normal distribution in these segregants, and suggested that the acetic acid tolerant traits were controlled by multiple quantitative trait loci (QTLs). Thus, 220 SSR markers covering the whole genome were used to detect QTLs of acetic acid tolerant traits. As a result, three QTLs were located on chromosomes 9, 12, and 16, respectively, which explained 38.8-65.9 % of the range of phenotypic variation. Furthermore, twelve genes of the candidates fell into the three QTL regions by integrating the QTL analysis with candidates of acetic acid tolerant genes. These results provided a novel avenue to obtain more robust strains.

Indexed as

Quantitative Trait LociAcetic AcidChromosome MappingDNA, FungalGenomicsMicrosatellite RepeatsPhenotypeQuantitative Trait, HeritableSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAcetic AcidDNA, FungalSaccharomyces cerevisiae ProteinsAcetic acid tolerancePhenotypic analysisQTLSaccharomyces cerevisiaeSSR markers

Identifiers

PMID27430512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.