ArticleObesity (Silver Spring, Md.)2016
Voxel-based morphometry reveals brain gray matter volume changes in successful dieters.
Article in Obesity (Silver Spring, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Network-Level Convergence of Adiposity-Related Gray Matter Alterations: A Coordinate-Based Connectome Mapping Meta-Analysis With Imaging Transcriptomics.Human brain mapping · 2026Pooled it
- Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010.Current obesity reports · 2023Pooled it
- Gray matter volume alterations in subjects with overweight and obesity: Evidence from a voxel-based meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Obesity is associated with reduced orbitofrontal cortex volume: A coordinate-based meta-analysis.NeuroImage. Clinical · 2020Pooled it
- Longitudinal surface-based morphometry reveals potential MRI biomarkers correlated with multidimensional brain health measures.Brain imaging and behavior · 2026Article
- Longitudinal Surface-Based Morphometry Reveals Potential MRI Biomarkers Correlated with Multidimensional Brain Health Measures.Research square · 2025Article
- The Interplay Between Psychological and Neurobiological Predictors of Weight Regain: A Narrative Review.Nutrients · 2025Review
- The effect of weight loss on brain age in schizophrenia spectrum disorders.PLOS mental health · 2025Article
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- Computational approaches to predicting treatment response to obesity using neuroimaging.Reviews in endocrine & metabolic disorders · 2022Review
- Altered Brain Structural Reorganization and Hierarchical Integrated Processing in Obesity.Frontiers in neuroscience · 2022Article
- Obesity as a Risk Factor for Accelerated Brain Ageing in First-Episode Psychosis-A Longitudinal Study.Schizophrenia bulletin · 2021Article
- The Impact of Restrictive and Non-restrictive Dietary Weight Loss Interventions on Neurobehavioral Factors Related to Body Weight Control: the Gaps and Challenges.Current obesity reports · 2021Review
- Strategies to Understand the Weight-Reduced State: Genetics and Brain Imaging.Obesity (Silver Spring, Md.) · 2021Review
- Cognitive Training: Associations and Implications for Weight Management and Translational Research.Translational journal of the American College of Sports Medicine · 2021Article
- Familial Obesity Risk and Current Excess Weight Influence Brain Structure in Adolescents.Obesity (Silver Spring, Md.) · 2021Article
- Patterns of Regional Cerebral Blood Flow as a Function of Obesity in Adults.Journal of Alzheimer's disease : JAD · 2020Article
- Higher Body-Mass Index and Lower Gray Matter Volumes in First Episode of Psychosis.Frontiers in psychiatry · 2020Article
- Whole-brain morphometric studies in alcohol addicts by voxel-based morphometry.Annals of translational medicine · 2019Article
- Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum.NeuroImage. Clinical · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo compare regional brain volume predictors of percent weight loss (WL) in dieters with obesity (DwO) and in the same participants categorized as "successful" (≥7% WL) or "unsuccessful" dieters (<7% WL).
methodsDwO (n = 72) and participants with healthy weight (n = 22) completed a structural MRI at baseline and 3 months. All DwO participants were enrolled in a 12-week program consisting of a reduced calorie diet, increased physical activity, and behavioral modification. SPM8-based voxel-based morphometry processing streams were used for measurements of regional gray (GMV) and white matter volume and longitudinal changes in volume. Correlations between WL and baseline brain volume and change in brain volume, as well as differences between groups, were then tested.
results%WL was positively correlated with baseline GMV in right parahippocampal and orbitofrontal gyri in DwO. Successful dieters showed greater GMV loss in the left precentral gyrus and the insula compared with unsuccessful dieters. A negative correlation was found between %WL and GMV change from baseline in the left prefrontal regions.
conclusionsFindings illustrate that WL is related to volumetric changes in brain areas previously linked to interoception and food motivation.
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