ArticleHIV medicine2016
Smoking and projected cardiovascular risk in an HIV-positive Asian regional cohort.
Article in HIV medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Association of human immunodeficiency virus with acute myocardial infarction and presumed sudden cardiac death.Resuscitation plus · 2025Article
- Comparison of smoking behaviors and associated factors between HIV-infected and uninfected men in Guilin, China: a case-control study.Frontiers in psychology · 2024Article
- Cardiovascular disease incidence projections in the TREAT Asia HIV Observational Database (TAHOD).Antiviral therapy · 2019Article
- Long-term clinical, immunological and virological outcomes of patients on antiretroviral therapy in southern Myanmar.PloS one · 2018Article
- Factors affecting affect cardiovascular health in Indonesian HIV patients beginning ART.AIDS research and therapy · 2017Article
- Cardiovascular risk in an HIV-infected population in India.Heart Asia · 2017Article
- Cardiovascular Disease and Cardiovascular Disease Risk in HIV-Positive Populations in the Asian Region.The open AIDS journal · 2017Article
Corrections and comments
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Authors and funding
22 authors at 18 institutions in 12 countries.
Funding
Abstract
objectivesThe aim of the study was to assess the prevalence and characteristics associated with current smoking in an Asian HIV-positive cohort, to calculate the predictive risks of cardiovascular disease (CVD), coronary heart disease (CHD) and myocardial infarction (MI), and to identify the impact that simulated interventions may have.
methodsLogistic regression analysis was used to distinguish associated current smoking characteristics. Five-year predictive risks of CVD, CHD and MI and the impact of simulated interventions were calculated utilizing the Data Collection on Adverse Effects of Anti-HIV Drugs Study (D:A:D) algorithm.
resultsSmoking status data were collected from 4274 participants and 1496 of these had sufficient data for simulated intervention calculations. Current smoking prevalence in these two groups was similar (23.2% vs. 19.9%, respectively). Characteristics associated with current smoking included age > 50 years compared with 30-39 years [odds ratio (OR) 0.65; 95% confidence interval (CI) 0.51-0.83], HIV exposure through injecting drug use compared with heterosexual exposure (OR 3.03; 95% CI 2.25-4.07), and receiving antiretroviral therapy (ART) at study sites in Singapore, South Korea, Malaysia, Japan and Vietnam in comparison to Thailand (all OR > 2). Women were less likely to smoke than men (OR 0.11; 95% CI 0.08-0.14). In simulated interventions, smoking cessation demonstrated the greatest impact in reducing CVD and CHD risk and closely approximated the impact of switching from abacavir to an alternate antiretroviral in the reduction of 5-year MI risk.
conclusionsMultiple interventions could reduce CVD, CHD and MI risk in Asian HIV-positive patients, with smoking cessation potentially being the most influential.
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