ArticleJournal of insect physiology
Optimization of wrMTrck to monitor Drosophila larval locomotor activity.
Article in Journal of insect physiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- dMyc suppresses CTG-induced cytotoxicity in the Drosophila model of DM1 by reducing autophagy and cell death.Cell death discovery · 2026Article
- Polycomb repression works without Siesta, theScience advances · 2026Article
- A Segment Anything Model-based tool for semi-automated behavioural analysis of Drosophila and other model organisms.Disease models & mechanisms · 2026Article
- Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Valve cells are crucial for efficient cardiac performance in Drosophila.PLoS genetics · 2025Article
- Mitochondrial ROS modulate presynaptic plasticity in the drosophila neuromuscular junction.Redox biology · 2025Article
- microRNA-184 distribution and consequences on glial septate junctions and the blood-brain barrier.PloS one · 2025Article
- Tyramine-Mediated Hyperactivity Modulates the Dietary Habits in Helicoverpa armigera.Journal of chemical ecology · 2024Article
- Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics.Cell reports · 2024Article
- Locomotor Assays in Drosophila Larvae and Adult Flies.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Drosophila melanogaster Neuromuscular Junction as a Model to Study Synaptopathies and Neuronal Autophagy.Methods in molecular biology (Clifton, N.J.) · 2024Article
- A Simple Method for Quantifying Larval Locomotion in Drosophila melanogaster.Methods in molecular biology (Clifton, N.J.) · 2024Article
- A Novel Drosophila-based Drug Repurposing Platform Identified Fingolimod As a Potential Therapeutic for TDP-43 Proteinopathy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Article
- G3'MTMD3 in the insect GABA receptor subunit, RDL, confers resistance to broflanilide and fluralaner.PLoS genetics · 2023Article
- High-resolution analysis of individualOpen biology · 2023Article
- Innexin-Mediated Adhesion between Glia Is Required for Axon Ensheathment in the Peripheral Nervous System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Article
- A Drosophila model of the neurological symptoms in Mpv17-related diseases.Scientific reports · 2022Article
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- A pathogenic mechanism associated with myopathies and structural birth defects involves TPM2-directed myogenesis.JCI insight · 2022Article
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Authors and funding
5 authors.
Funding
Abstract
An efficient and low-cost method of examining larval movement in Drosophila melanogaster is needed to study how mutations and/or alterations in the muscular, neural, and olfactory systems affect locomotor behavior. Here, we describe the implementation of wrMTrck, a freely available ImageJ plugin originally developed for examining multiple behavioral parameters in the nematode C. elegans. Our optimized method is rapid, reproducible and does not require automated microscope setups or the purchase of proprietary software. To demonstrate the utility of this method, we analyzed the velocity and crawling paths of two Drosophila mutants that affect muscle structure and/or function. Additionally, we show that this approach is useful for tracking the behavior of adult insects, including Tribolium castaneum and Drosophila melanogaster.
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