Evidence map›Paper›PMID 27429790›Full record

ArticleEuropean journal of microbiology & immunology2016

Toxoplasma Gondii Infection and Depression: A Case-Control Seroprevalence Study.

Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Luis Omar Berumen-Segovia, Yazmin Elizabeth Torres-Prieto, Sergio Estrada-Martínez, Alma Rosa Pérez-Álamos, María Nalleli Ortiz-Jurado, Gabriel Molotla-de-León, Isabel Beristain-García and 2 more

Open access · diamondAbstract read
In one paragraph

Article in European journal of microbiology & immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Life (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Global seroprevalence ofHealth science reports · 2023
    Article
  9. Article
  10. Medicina (Kaunas, Lithuania) · 2022
    Article
  11. Article
  12. Article
  13. Association betweenPathogens (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Neurological and Neurobehavioral Disorders Associated withJournal of parasitology research · 2021
    Review
  16. Frontiers in psychiatry · 2021
    Review
  17. Article
  18. Article
  19. The Association between Suicide Attempts andClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Cosme Alvarado-EsquivelFaculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Dgo, Mexico.
Luis Francisco Sánchez-AnguianoInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State. Avenida Universidad S/N , 34000 Durango, Durango, Mexico.
Jesús Hernández-TinocoInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State. Avenida Universidad S/N , 34000 Durango, Durango, Mexico.
Luis Omar Berumen-SegoviaFaculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N , 34000 Durango, Dgo, Mexico.
Yazmin Elizabeth Torres-PrietoFacultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico.
Sergio Estrada-MartínezInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State. Avenida Universidad S/N , 34000 Durango, Durango, Mexico.
Alma Rosa Pérez-ÁlamosInstitute for Scientific Research "Dr. Roberto Rivera Damm," Juárez University of Durango State. Avenida Universidad S/N , 34000 Durango, Durango, Mexico.
María Nalleli Ortiz-JuradoHospital of Mental Health "Dr. Miguel Vallebueno", Servicios de Salud de Durango , Durango, Mexico.
Gabriel Molotla-de-LeónHospital of Mental Health "Dr. Miguel Vallebueno", Servicios de Salud de Durango , Durango, Mexico.
Isabel Beristain-GarcíaFacultad de Enfermería y Obstetricia, Juárez University of Durango State , Cuauhtémoc 223 norte, 34000 Durango, Mexico.
Elizabeth Rábago-SánchezFaculty of Medicine and Nutrition, Juárez University of Durango State, Avenida Universidad S/N, 34000 Durango, Dgo, Mexico; General Hospital, Secretary of Health, Avenida 5 de febrero 220, 34000 Durango, Mexico.
Oliver LiesenfeldInstitute for Microbiology and Hygiene, Campus Benjamin Franklin, Charité Medical School , Hindenburgdamm 27, D-12203 Berlin, Germany.
Universidad Juárez del Estado de Durango · MXUniversidad del Valle de Guadiana · MXCharité - Universitätsmedizin Berlin · DEDurango Institute of Technology · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the association of Toxoplasma gondii infection and depression in a sample of psychiatric patients and control subjects without depression. We performed an age- and gender-matched case-control study of 89 patients suffering from depression attended in a public psychiatric hospital in Durango City, Mexico and 356 control subjects without depression from the general population of the same city. Participants were tested for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays. Anti-T. gondii IgG antibodies were found in 11 (12.4%) of the 89 cases and in 22 (6.2%) of the 356 controls (OR = 2.14; 95% CI: 1.00-4.59; P = 0.04). Anti-T. gondii IgM antibodies were found in four (19%) of 21 anti-T. gondii IgG seropositive controls but not in 11 anti-T. gondii IgG seropositive cases (P = 0.27). Patients aged 30 years old and younger had a significantly higher seroprevalence of T. gondii infection than controls of the same age group (P = 0.001). Results of the present study suggest a potential association between T. gondii infection and depression. Furthers studies to confirm our results and to determine the epidemiology of T. gondii in young depressed patients should be conducted.

Indexed as

case–control studydepressionpsychiatric patientsseroprevalenceToxoplasmagondii

Identifiers

PMID27429790
PMCPMC4936330
OpenAlexW2344555407

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.