Evidence map›Paper›PMID 27429754›Full record

ArticleJournal of materials chemistry. B2016

Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms.

Jiayi Zhou, Benjamin Horev, Geelsu Hwang, Marlise I Klein, Hyun Koo, Danielle S W Benoit

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
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  10. Drug delivery strategies for antibiofilm therapy.Nature reviews. Microbiology · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. pH-activated antibiofilm strategies for controlling dental caries.Frontiers in cellular and infection microbiology · 2023
    Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Jiayi ZhouDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Benjamin HorevDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Geelsu HwangBiofilm Research Lab, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Marlise I KleinDepartment of Dental Materials and Prosthodontics, Araraquara Dental School, Univ Estadual Paulista, UNESP, Sao Paulo, Brazil.
Hyun KooBiofilm Research Lab, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthodontics and Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Danielle S W BenoitDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA; Department of Chemical Engineering, University of Rochester, Rochester, NY, USA; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
University of Rochester · USCalifornia University of Pennsylvania · USCentro Universitário de Araraquara · BRPhiladelphia University · US

Funding

Evaluation of a Novel Anti-Caries Approach to Modulate Virulence of S. mutansR01DE018023 · NIDCR · UNIVERSITY OF ROCHESTER · PI KOO, HYUN · 2008 to 2019
$3.4M
Women's Health and the Environment over the Entire Lifespan (WHEEL)K12ES019852 · NIEHS · UNIVERSITY OF ROCHESTER · PI CORY-SLECHTA, DEBORAH A · 2010 to 2014
$1.8M
NIDCR NIH HHS R01 DE018023NIEHS NIH HHS K12 ES019852
6 · The paper itself

Abstract

We previously reported on cationic, pH-responsive p(DMAEMA)-

Identifiers

PMID27429754
PMCPMC4943847
OpenAlexW2179749390

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.