Evidence map›Paper›PMID 27429614›Full record

ReviewAdvances in urology2016

From Inflammation to Prostate Cancer: The Role of Inflammasomes.

Dev Karan, Seema Dubey

Open access · goldAbstract readReview
In one paragraph

Review in Advances in urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Divergent functions of NLRP3 inflammasomes in cancer: a review.Cell communication and signaling : CCS · 2023
    Review
  6. Review
  7. Article
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  10. Article
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  12. Article
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  15. Article
  16. Exploring the Nutraceutical Potential of Dried PepperAntioxidants (Basel, Switzerland) · 2020
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dev KaranDepartment of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, SC 29208, USA.ORCID 0000-0002-0905-0886
Seema DubeyDepartment of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, SC 29208, USA.
University of South Carolina · US

Funding

Targeting early ceramide elevation in pre-symptomatic eczemaP20GM103641 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ENOS, REILLY, NAGARKATTI, PRAKASH S · 2012 to 2023
$20.7M
Modulation of NK cell activity by dietary product for prostate cancer preventionR21CA169453 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARAN, DEV · 2012 to 2013
$351k
Racial disparity of MIC-1 gene in prostate tumor biologyR21CA179733 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARAN, DEV · 2014 to 2015
$319k
NCI NIH HHS R21 CA169453NCI NIH HHS R21 CA179733NIGMS NIH HHS P20 GM103641
6 · The paper itself

Abstract

Inflammation-associated studies entice specific attention due to inflammation's role in multiple stages of prostate cancer development. However, mechanistic regulation of inflammation inciting prostate cancer remains largely uncharacterized. A focused class of inflammatory regulators known as inflammasomes has recently gained attention in cancer development. Inflammasomes are a multiprotein complex that drives a cascade of proinflammatory cytokines regulating various cellular activities. Inflammasomes activation is linked with infection, stress, or danger signals, which are common events within the prostate gland. In this study, we review the potential of inflammasomes in understanding the role of inflammation in prostate cancer.

Identifiers

PMID27429614
PMCPMC4939357
OpenAlexW2474283142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.