Evidence map›Paper›PMID 27429543›Full record

ArticleIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society

Magnetic and Plasmonic Contrast Agents in Optical Coherence Tomography.

Amy L Oldenburg, Richard L Blackmon, Justin M Sierchio

Abstract read
In one paragraph

Article in IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Diffusion tensor optical coherence tomography.Physics in medicine and biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Amy L OldenburgDepartment of Physics and Astronomy, the Department of Biomedical Engineering, and the Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 USA.
Richard L BlackmonDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 USA.
Justin M SierchioDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3255 USA.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Developing Contrast-Enhanced Ultrasound of Thrombosis via SPIO-RL PlateletsR21HL119928 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLDENBURG, AMY L · 2014 to 2015
$411k
Development of a method for in situ nanorheology of human airway mucusR21HL111968 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OLDENBURG, AMY L · 2012 to 2013
$392k
NHLBI NIH HHS R21 HL111968NHLBI NIH HHS R21 HL119928NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Optical coherence tomography (OCT) has gained widespread application for many biomedical applications, yet the traditional array of contrast agents used in incoherent imaging modalities do not provide contrast in OCT. Owing to the high biocompatibility of iron oxides and noble metals, magnetic and plasmonic nanoparticles, respectively, have been developed as OCT contrast agents to enable a range of biological and pre-clinical studies. Here we provide a review of these developments within the past decade, including an overview of the physical contrast mechanisms and classes of OCT system hardware addons needed for magnetic and plasmonic nanoparticle contrast. A comparison of the wide variety of nanoparticle systems is also presented, where the figures of merit depend strongly upon the choice of biological application.

Indexed as

Contrast agentsmagnetomotiveoptical coherence tomographyplasmonic nanoparticlessuperparamagnetic iron oxides

Identifiers

PMID27429543
PMCPMC4941814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.