ArticleTetrahedron2016
Second Generation Modifiers of Colistin Resistance Show Enhanced Activity and Lower Inherent Toxicity.
Article in Tetrahedron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 17 citations in OpenAlex.
- Review
- An integrated system of micromixers and microfluidic concentration gradient chips assisted drug screening over large concentration range.Mikrochimica acta · 2026Article
- Article
- Untying the anchor for the lipopolysaccharide: lipid A structural modification systems offer diagnostic and therapeutic options to tackle polymyxin resistance.Arhiv za higijenu rada i toksikologiju · 2023Review
- Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants.ACS infectious diseases · 2021Article
- Antibiotic Adjuvant Activity Revealed in a Photoaffinity Approach to Determine the Molecular Target of Antipyocyanin Compounds.ACS infectious diseases · 2021Article
- A Whole-Cell Screen Identifies Small Bioactives That Synergize with Polymyxin and Exhibit Antimicrobial Activities against Multidrug-Resistant Bacteria.Antimicrobial agents and chemotherapy · 2020Article
- Structure-Function Studies on IMD-0354 Identifies Highly Active Colistin Adjuvants.ChemMedChem · 2020Article
- Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-Negative Bacteria.ACS infectious diseases · 2019Article
- Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin.ACS medicinal chemistry letters · 2019Article
- Identification of Anti-Mycobacterial Biofilm Agents Based on the 2-Aminoimidazole Scaffold.ChemMedChem · 2019Article
- Tryptamine derivatives disarm colistin resistance in polymyxin-resistant gram-negative bacteria.Bioorganic & medicinal chemistry · 2019Article
- Signal Transduction Proteins inFrontiers in microbiology · 2019Review
- New Class of Adjuvants Enables Lower Dosing of Colistin Against Acinetobacter baumannii.ACS infectious diseases · 2018Article
- Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria.Bioorganic & medicinal chemistry · 2017Article
- Marine sponge alkaloids as a source of anti-bacterial adjuvants.Bioorganic & medicinal chemistry letters · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
We recently reported a 2-aminoimidazole-based antibiotic adjuvant that reverses colistin resistance in two species of Gram-negative bacteria. Mechanistic studies in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.