Evidence map›Paper›PMID 27429185›Full record

SynthesisJournal of acquired immune deficiency syndromes (1999)2016

Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People.

Tonia Poteat, Ayden Scheim, Jessica Xavier, Sari Reisner, Stefan Baral

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05323695 (Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand), which is not on this map. Cited by 260 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
260citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05323695 nacompletednot on this mapstarted 2021, after this paper: background citation

Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand

TypeinterventionalSponsorThai Red Cross AIDS Research CentreRan2021 to 2024Enrolled317ConditionsDepressive SymptomsArmsDepression Screening Intervention
3 · Its place in the literature

Who cites it

260 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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200 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tonia Poteat*Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; †Department of Epidemiology and Biostatistics, Western University, London, Canada; ‡U.S. Department of Health and Human Services, Health Resources and Services Administration, Rockville, Maryland; and §Boston Children's Hospital/Harvard Medical School, Harvard T.H. Chan School of Public Health, Boston, MA.
Ayden Scheim
Jessica Xavier
Sari Reisner
Stefan Baral

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
TransPrEP: Social Network-Based PrEP Adherence for Transgender Women in PeruR34MH104072 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CLARK, JESSE LAWTON, MIMIAGA, MATTHEW JAMES · 2014 to 2016
$672k
NIAID NIH HHS P30 AI094189NICHD NIH HHS R25 HD045810NIMH NIH HHS R34 MH104072
6 · The paper itself

Abstract

introductionTransgender populations have been underrepresented in HIV epidemiologic studies and consequently in HIV prevention, care, and treatment programs. Since 2012, there has been a dramatic increase in research focused on transgender people. Studies highlight the burden of HIV and risk determinants, including intersecting stigmas, as drivers of syndemics among transgender populations. This review synthesizes the most recent global epidemiology of HIV infection and describes current gaps in research and interventions to inform prioritization of HIV research for transgender populations.

methodsA systematic review was conducted of the medical literature published between January 1, 2012 and November 30, 2015. The data focused on HIV prevalence, determinants of risk, and syndemics among transgender populations.

resultsEstimates varied dramatically by location and subpopulation. Transfeminine individuals have some of the highest concentrated HIV epidemics in the world with laboratory-confirmed prevalence up to 40%. Data were sparse among trans masculine individuals; however, they suggest potential increased risk for trans masculine men who have sex with men (MSM). No prevalence data were available for transgender people across Sub-Saharan Africa or Eastern Europe/Central Asia. Emerging data consistently support the association of syndemic conditions with HIV risk in transgender populations. DISCUSSION: Addressing syndemic conditions and gender-specific challenges is critical to ensure engagement and retention in HIV prevention by transgender populations. Future research should prioritize: filling knowledge gaps in HIV epidemiology; elucidating how stigma shapes syndemic factors to produce HIV and other deleterious effects on transgender health; and understanding how to effectively implement HIV interventions for transgender people.

Indexed as

Global HealthTransgender PersonsDepressionEpidemicsFemaleHIV InfectionsHumansInterpersonal RelationsMalePrevalenceRisk FactorsSexual PartnersSocial EnvironmentSocial StigmaSubstance-Related DisordersUnsafe Sex

Identifiers

PMID27429185
PMCPMC4969059

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.