ArticleHealthcare (Basel, Switzerland)2013
Detection and Discrimination of Non-Melanoma Skin Cancer by Multimodal Imaging.
Article in Healthcare (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Advancing Label-Free Imaging Through CARS Microscopy: From Signal Formation to Biological Interpretation.International journal of molecular sciences · 2026Review
- Non-invasive Imaging Techniques: From Histology to In-vivo Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Advanced Microscopy Techniques.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- In vivo and ex vivo sonographic evaluation of tumor margins during micrographic-controlled surgery: a promising new tool in dermato-oncology?Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Article
- Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation.Nature communications · 2025Article
- Endomicroscopic AI-driven morphochemical imaging and fs-laser ablation for selective tumor identification and selective tissue removal.Science advances · 2024Article
- Multi-Wavelength Raman Differentiation of Malignant Skin Neoplasms.International journal of molecular sciences · 2024Article
- From Vibrations to Visions: Raman Spectroscopy's Impact on Skin Cancer Diagnostics.Journal of clinical medicine · 2023Review
- Comparison of denoising tools for the reconstruction of nonlinear multimodal images.Biomedical optics express · 2023Article
- Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation.Journal of biomedical optics · 2023Article
- Identification of different types of tumors based on photoacoustic spectral analysis: preclinical feasibility studies on skin tumors.Journal of biomedical optics · 2023Article
- Management of Non-Melanoma Skin Cancer: Radiologists Challenging and Risk Assessment.Diagnostics (Basel, Switzerland) · 2023Review
- Label-free multimodal imaging of infected Galleria mellonella larvae.Scientific reports · 2022Article
- Photoacoustic imaging of periorbital skin cancerBiomedical optics express · 2022Article
- Preoperative AI-Driven Fluorescence Diagnosis of Non-Melanoma Skin Cancer.Diagnostics (Basel, Switzerland) · 2021Article
- Identification of inflammatory markers in eosinophilic cells of the immune system: fluorescence, Raman and CARS imaging can recognize markers but differently.Cellular and molecular life sciences : CMLS · 2021Article
- Multimodal nonlinear endomicroscopic imaging probe using a double-core double-clad fiber and focus-combining micro-optical concept.Light, science & applications · 2021Article
- Computational tissue staining of non-linear multimodal imaging using supervised and unsupervised deep learning.Biomedical optics express · 2021Article
- Article
- Efficiency of long-term high-dose intravenous ascorbic acid therapy in locally advanced basal cell carcinoma - a pilot study.Postepy dermatologii i alergologii · 2020Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-melanoma skin cancer (NMSC) belongs to the most frequent human neoplasms. Its exposed location facilitates a fast ambulant treatment. However, in the clinical practice far more lesions are removed than necessary, due to the lack of an efficient pre-operational examination procedure: Standard imaging methods often do not provide a sufficient spatial resolution. The demand for an efficient in vivo imaging technique might be met in the near future by non-linear microscopy. As a first step towards this goal, the appearance of NMSC in various microspectroscopic modalities has to be defined and approaches have to be derived to distinguish healthy skin from NMSC using non-linear optical microscopy. Therefore, in this contribution the appearance of ex vivo NMSC in a combination of coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG) and two photon excited fluorescence (TPEF) imaging-referred as multimodal imaging-is described. Analogous to H&E staining, an overview of the distinct appearances and features of basal cell and squamous cell carcinoma in the complementary modalities is derived, and is expected to boost in vivo studies of this promising technological approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.