Evidence map›Paper›PMID 27428984›Full record

ArticleMarine drugs2016

Chamigrane Sesquiterpenes from a Basidiomycetous Endophytic Fungus XG8D Associated with Thai Mangrove Xylocarpus granatum.

Siwattra Choodej, Thapong Teerawatananond, Tohru Mitsunaga, Khanitha Pudhom

Abstract read
In one paragraph

Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Endophytic fungi: A treasure trove of novel anticancer compounds.Current research in pharmacology and drug discovery · 2021
    Article
  7. Review
  8. Article
  9. Spirocyclic Motifs in Natural Products.Molecules (Basel, Switzerland) · 2019
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siwattra ChoodejThe United Graduate School of Agricultural Science, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. csiwattra@hotmail.com.
Thapong TeerawatananondFaculty of Science and Technology, Valaya Alongkorn Rajabhat University under Royal Patronage, Pathumtani 13138, Thailand. thapong_sthc@hotmail.com.
Tohru MitsunagaThe United Graduate School of Agricultural Science, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan. mitunaga@gifu-u.ac.jp.
Khanitha PudhomDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Khanitha.P@chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Six new chamigrane sesquiterpenes, merulinols A‒F (1‒6), and four known metabolites (7‒10) were isolated from the culture of the basidiomycetous fungus XG8D, a mangrove-derived endophyte. Their structures were elucidated mainly by 1D and 2D NMR, while the structures of 1 and 2 were further confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxicity of all compounds was evaluated against three human cancer cell lines, MCF-7, Hep-G2, and KATO-3. Compounds 3 and 4 selectively displayed cytotoxicity against KATO-3 cells with IC50 values of 35.0 and 25.3 μM, respectively.

Indexed as

BasidiomycotaCell Line, TumorCrystallography, X-RayDrug Screening Assays, AntitumorEndophytesFungiHep G2 CellsHumansMCF-7 CellsMolecular StructureRhizophoraceaeSesquiterpenesThailandX-Ray DiffractionSesquiterpeneschamigranecytotoxicendophytic fungussesquiterpene

Identifiers

PMID27428984
PMCPMC4962022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.