ReviewInternational journal of molecular sciences2016
Modifications in Glass Ionomer Cements: Nano-Sized Fillers and Bioactive Nanoceramics.
Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Secondary caries and marginal adaptation of ion-releasing versus resin composite restorations: a systematic review and meta-analysis of randomized clinical trials.Scientific reports · 2022Pooled it
- Effects of Additive Incorporation on Fluoride Release of Orthodontic Glass Ionomer Cements and Adhesives: A Systematic Review.Materials (Basel, Switzerland) · 2026Review
- Effect of Nanodiamond Incorporation on the Surface, Mechanical, and Tribological Properties of Glass Ionomer Cement.Journal of functional biomaterials · 2026Article
- Effect of Titanium Dioxide (TiOMaterials (Basel, Switzerland) · 2026Review
- Dose- and time-dependent cytotoxic responses of contemporary glass ionomer cements: an in vitro study.BMC oral health · 2026Article
- Fabrication and characterization of poly methyl methacrylate (PMMA) matrix modified with strontium nano-rods.Scientific reports · 2026Article
- In vitro assessment of cytotoxic, genotoxic, and antimicrobial properties of pediatric restorative dental materials.BMC oral health · 2025Article
- Evaluation of bioactive glass primer on dentin bonding durability and interface properties.BMC oral health · 2025Article
- Synthesis, structural, and characterization of polymethylmethacrylate matrix-ZnO nanocomposite.Scientific reports · 2025Article
- Article
- Comparative Assessment of Microleakage in Nanoformulated and Conventional Glass Ionomer Cement under Simulated Aging: A Stereomicroscopic Study.International journal of clinical pediatric dentistry · 2025Article
- Evaluation of Factors Affecting Fluoride Release from Dental Sealants: A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- Evaluating immunohistochemical and genetic expression of green-mediated nano-enhanced glass ionomer cement: An animal model study.Journal of conservative dentistry and endodontics · 2025Article
- Evaluation of Structural Characterization and Biocompatibility of Glass Ionomer Cement Enhanced with Nanocomposites of Chitosan, Titanium, Zirconium, and Hydroxyapatite: Assessment of Cell Viability and Adhesion through Gingival Fibroblast Cell Line.International journal of clinical pediatric dentistry · 2025Article
- Bond strength durability of three bioactive restorative materials to silver diamine fluoride treated artificially demineralized dentine.BMC oral health · 2025Article
- The Impact of Environmental and Material Factors on Fluoride Release from Metal-Modified Glass Ionomer Cements: A Systematic Review of In Vitro Studies.Materials (Basel, Switzerland) · 2025Review
- Minimally Invasive Techniques for Managing Dental Caries in Children: Efficacy, Applications, and Future Directions.Cureus · 2025Review
- Influence of luting cement on the biomechanical behavior of Bioflx crowns.BMC oral health · 2025Article
- Effects of Thermocycling on Antimicrobial Activity, Contact Angle, Surface Roughness, and Microhardness of Nanomodified Glass Ionomer Cement: AnInternational journal of clinical pediatric dentistry · 2025Article
- A Comparative Evaluation of Bonding Strength, Tensile Strength, and Microleakage of GC Hybrid Cement with Micro- and Nano-hydroxyapatite: AnInternational journal of clinical pediatric dentistry · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glass ionomer cements (GICs) are being used for a wide range of applications in dentistry. In order to overcome the poor mechanical properties of glass ionomers, several modifications have been introduced to the conventional GICs. Nanotechnology involves the use of systems, modifications or materials the size of which is in the range of 1-100 nm. Nano-modification of conventional GICs and resin modified GICs (RMGICs) can be achieved by incorporation of nano-sized fillers to RMGICs, reducing the size of the glass particles, and introducing nano-sized bioceramics to the glass powder. Studies suggest that the commercially available nano-filled RMGIC does not hold any significant advantage over conventional RMGICs as far as the mechanical and bonding properties are concerned. Conversely, incorporation of nano-sized apatite crystals not only increases the mechanical properties of conventional GICs, but also can enhance fluoride release and bioactivity. By increasing the crystallinity of the set matrix, apatites can make the set cement chemically more stable, insoluble, and improve the bond strength with tooth structure. Increased fluoride release can also reduce and arrest secondary caries. However, due to a lack of long-term clinical studies, the use of nano-modified glass ionomers is still limited in daily clinical dentistry. In addition to the in vitro and in vivo studies, more randomized clinical trials are required to justify the use of these promising materials. The aim of this paper is to review the modification performed in GIC-based materials to improve their physicochemical properties.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.