Evidence map›Paper›PMID 27428774›Full record

ArticleNature structural & molecular biology2016

CATCHR, HOPS and CORVET tethering complexes share a similar architecture.

Hui-Ting Chou, Danijela Dukovski, Melissa G Chambers, Karin M Reinisch, Thomas Walz

Open access · greenAbstract read
In one paragraph

Article in Nature structural & molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
  2. Review
  3. GARP Complex in Golgi Physiology.Sub-cellular biochemistry · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The machinery of vesicle fusion.Current opinion in cell biology · 2023
    Review
  11. Article
  12. Role of GARP Vesicle Tethering Complex in Golgi Physiology.International journal of molecular sciences · 2023
    Review
  13. Article
  14. SNARE Proteins in Synaptic Vesicle Fusion.Advances in neurobiology · 2023
    Article
  15. Review
  16. Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hui-Ting ChouDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-8693-8571
Danijela DukovskiDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Melissa G ChambersDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Karin M ReinischDepartment of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, USA.
Thomas WalzDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.
Harvard University · USYale University · US

Funding

Single particle reconstructionP01GM062580 · NIGMS · HARVARD MEDICAL SCHOOL · PI HARRISON, STEPHEN COPLAN · 2001 to 2016
$23.7M
Regulatory Mechanisms in Membrane TraffickingR01GM080616 · NIGMS · YALE UNIVERSITY · PI REINISCH, KARIN M · 2007 to 2018
$4.1M
NIGMS NIH HHS P01 GM062580NIGMS NIH HHS R01 GM080616
6 · The paper itself

Abstract

We show here that the Saccharomyces cerevisiae GARP complex and the Cog1-4 subcomplex of the COG complex, both members of the complexes associated with tethering containing helical rods (CATCHR) family of multisubunit tethering complexes, share the same subunit organization. We also show that HOPS, a tethering complex acting in the endolysosomal pathway, shares a similar architecture, thus suggesting that multisubunit tethering complexes use related structural frameworks.

Indexed as

Adaptor Proteins, Vesicular TransportMembrane Transport ProteinsMicroscopy, ElectronModels, MolecularMultiprotein ComplexesProtein Structure, QuaternaryProtein SubunitsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsAdaptor Proteins, Vesicular TransportCog1 protein, S cerevisiaeCOG2 protein, S cerevisiaeCOG3 protein, S cerevisiaeCOG4 protein, S cerevisiaeMembrane Transport ProteinsMultiprotein ComplexesProtein SubunitsSaccharomyces cerevisiae ProteinsVesicular Transport Proteins

Identifiers

PMID27428774
PMCPMC4972687
OpenAlexW2493174924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.