ArticleNature genetics2016
Exome sequencing of geographically diverse barley landraces and wild relatives gives insights into environmental adaptation.
Article in Nature genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 1 of them a synthesis that pooled it.
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Who cites it
155 citing papers in PubMed, 1 synthesis or guideline pooled it.
- New loci and candidate genes in spring two-rowed barley detected through meta-analysis of a field trial European network.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Pooled it
- Haplotype Blocks Are Associated With Rapid Local Adaptation to Environmental Shifts in Wild Barley.Molecular ecology · 2026Article
- Nanopore sequencing reveals coordinated host and microbiome responses across barley genotypes.BMC biology · 2026Article
- Integrated Comparative Genomics and Population Genomics Reveal the Genomic and Epigenomic Basis of Barley (Plants (Basel, Switzerland) · 2026Article
- A leucine-rich-repeat receptor-like kinase SERL1 phosphorylates and stabilizes OsALDH2B1 to promote alkaline tolerance and grain size in rice.Journal of integrative plant biology · 2026Article
- Decoding the Genetic Basis of Salinity Tolerance at Germination and Seedling Traits in HEB-25 Barley NAM Population.Plants (Basel, Switzerland) · 2026Article
- Wild barley cytoplasms reduce grain weight plasticity, with environment-dependent cytonuclear epistasis at theMolecular breeding : new strategies in plant improvement · 2026Article
- Identification of adaptive selection footprints and adaptation strategies of hulless barley (Hordeum vulgare var. coeleste) on the Qinghai-Tibet Plateau.BMC genomics · 2026Article
- Genetic dissection of root traits in barley identifies major QTLs and domestication signature.Plant cell reports · 2026Article
- Functional genomic map of local adaptation in sorghum to guide allele mining.bioRxiv : the preprint server for biology · 2026Article
- Population and pangenome analyses uncover the evolutionary dynamics of the peroxidase gene family in barley.BMC genomics · 2026Article
- Introgression of wild barley alleles improves seedlings salinity tolerance in the nested association mapping HEB-400 population.The plant genome · 2026Article
- The Evolution and Origin of Allotetraploid Aegilops geniculata Revealed by the Homoeolog-Resolved Genome Assembly.Plant biotechnology journal · 2026Article
- From dormant grain to beer: Unraveling barley's germination secret at the MKK3 locus.Plant communications · 2026Article
- Unveiling the Genomic Architecture of Phenotypic Plasticity Using Multiple GWAS Approaches Under Contrasting Conditions of Water Availability: A Model for Barley.International journal of molecular sciences · 2026Article
- Whole-genome resequencing of the wild barley diversity collection: a resource for identifying and exploiting genetic variation for cultivated barley improvement.G3 (Bethesda, Md.) · 2026Article
- Article
- Temporal regulation of gene expression during auxin-triggered crown root formation in barley: an integrated approach.Plant & cell physiology · 2025Article
- On the origin of the late-flowering ppd-H1 allele in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Using landscape genomics to infer genomic regions involved in environmental adaptation of soybean genebank accessions.BMC plant biology · 2025Article
95 more citing papers are in PubMed but not listed here.
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Authors and funding
21 authors.
Funding
Abstract
After domestication, during a process of widespread range extension, barley adapted to a broad spectrum of agricultural environments. To explore how the barley genome responded to the environmental challenges it encountered, we sequenced the exomes of a collection of 267 georeferenced landraces and wild accessions. A combination of genome-wide analyses showed that patterns of variation have been strongly shaped by geography and that variant-by-environment associations for individual genes are prominent in our data set. We observed significant correlations of days to heading (flowering) and height with seasonal temperature and dryness variables in common garden experiments, suggesting that these traits were major drivers of environmental adaptation in the sampled germplasm. A detailed analysis of known flowering-associated genes showed that many contain extensive sequence variation and that patterns of single- and multiple-gene haplotypes exhibit strong geographical structuring. This variation appears to have substantially contributed to range-wide ecogeographical adaptation, but many factors key to regional success remain unidentified.
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