ArticleNature genetics2016
Genomic analysis of 6,000-year-old cultivated grain illuminates the domestication history of barley.
Article in Nature genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 166 citations in OpenAlex.
- Historical Plant Embryos as Alternative Sources of Ancient DNA for Whole Genome Sequencing.Molecular ecology resources · 2026Article
- Ancient wheat DNA: How and what for?Journal, genetic engineering & biotechnology · 2026Article
- Ancient grains illuminate the mosaic origin of domesticated wheat.Nature plants · 2026Article
- A tale of two agricultural revolutions: crop introductions in the long 1st millennium ce southern Levant.Vegetation history and archaeobotany · 2026Review
- Year-round hourly temperature and humidity sensor readings from arid caves, Judean Desert, Israel.Scientific data · 2025Article
- Article
- Optimizing ancient DNA recovery from archaeological plant seeds.Scientific reports · 2025Article
- Tillering plasticity of drought-stressed barley genotypes under different re-watering regimes.BMC plant biology · 2025Article
- On the origin of the late-flowering ppd-H1 allele in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Effects of using deep learning to predict the geographic origin of barley genebank accessions on genome-environment association studies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Sequencing of historical plastid genomes reveal exceptional genetic diversity in early domesticated rye plants.iScience · 2025Article
- Genetic erosion in domesticated barley and a hypothesis of a North African centre of diversity.Ecology and evolution · 2024Article
- Are cereal grasses a single genetic system?Nature plants · 2024Article
- Unraveling the diversity and cultural heritage of fruit crops through paleogenomics.Trends in genetics : TIG · 2024Review
- Future-Proofing Agriculture: De Novo Domestication for Sustainable and Resilient Crops.International journal of molecular sciences · 2024Review
- Tracking population structure and phenology through time using ancient genomes from waterlogged white oak wood.Molecular ecology · 2024Article
- Can models of evolutionary transition clarify the debates over the Neolithic Revolution?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Identification of a candidate dwarfing gene in Pallas, the first commercial barley cultivar generated through mutational breeding.Frontiers in genetics · 2023Article
- Triticeae crop genome biology: an endless frontier.Frontiers in plant science · 2023Review
- Article
Corrections and comments
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Authors and funding
22 authors at 11 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cereal grass barley was domesticated about 10,000 years before the present in the Fertile Crescent and became a founder crop of Neolithic agriculture. Here we report the genome sequences of five 6,000-year-old barley grains excavated at a cave in the Judean Desert close to the Dead Sea. Comparison to whole-exome sequence data from a diversity panel of present-day barley accessions showed the close affinity of ancient samples to extant landraces from the Southern Levant and Egypt, consistent with a proposed origin of domesticated barley in the Upper Jordan Valley. Our findings suggest that barley landraces grown in present-day Israel have not experienced major lineage turnover over the past six millennia, although there is evidence for gene flow between cultivated and sympatric wild populations. We demonstrate the usefulness of ancient genomes from desiccated archaeobotanical remains in informing research into the origin, early domestication and subsequent migration of crop species.
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