Evidence map›Paper›PMID 27428203›Full record

ArticleMedicine2016

Effect of postural changes on cardiovascular parameters across gender.

Kieran Patel, Andreas Rössler, Helmut Karl Lackner, Irhad Trozic, Charles Laing, David Lorr, David A Green, Helmut Hinghofer-Szalkay, Nandu Goswami

Abstract read
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kieran PatelGravitational Physiology and Medicine Research Unit, Institute of Physiology, Medical University of Graz, Graz, Austria Kings College, London, UK Department of Neurophsiology, University of Linkoping, Sweden Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany.
Andreas Rössler
Helmut Karl Lackner
Irhad Trozic
Charles Laing
David Lorr
David A Green
Helmut Hinghofer-Szalkay
Nandu Goswami

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe investigated the effect of postural changes on various cardiovascular parameters across gender. Twenty-eight healthy subjects (16 male, 12 female) were observed at rest (supine) and subjected to 3 interventions; head-down tilt (HDT), HDT with lower body negative pressure (HDT+ LBNP at -30 mm Hg), and head-up tilt (HUT), each for 10 minutes separated by a 10 minutes recovery period.

methodsMeasurements were recorded for heart rate (HR), standard deviation of the normal-to-normal intervals, root mean square of successive differences between the normal-to-normal intervals, heart rate variability-low frequency (LFRRI), heart rate variability-high frequency (HFRRI), low frequency/high frequency ratio (LFRRI/HFRRI), systolic blood pressure (SBP), mean arterial pressure (MAP), diastolic blood pressure (DBP), total peripheral resistance index (TPRI), stroke index (SI), cardiac index (CI), index of contractility (IC), left ventricular work index, and left ventricular ejection time.

resultsAcross all cardiovascular parameters, there was a significant main effect of the intervention applied but there was no significant main effect of gender across all parameters.

conclusionsThe results suggest that there are no specific gender differences in regards to the measured variables under the conditions of this study. Furthermore, these results suggest that in healthy subjects, there appears to be evidence that LBNP partially elicits similar cardiovascular responses to HUT, which supports the use of LBNP as an intervention to counteract the effects of central hypovolemia.

Indexed as

AdultBlood PressureFemaleHead-Down TiltHealthy VolunteersHeart Function TestsHeart RateHumansMalePostureSex FactorsVascular Resistance

Identifiers

PMID27428203
PMCPMC4956797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.