Evidence map›Paper›PMID 27427799›Full record

ArticleDevelopment and psychopathology2016

Predicting substance use in emerging adulthood: A genetically informed study of developmental transactions between impulsivity and family conflict.

Kit K Elam, Frances L Wang, Kaitlin Bountress, Laurie Chassin, Danielle Pandika, Kathryn Lemery-Chalfant

Abstract read
In one paragraph

Article in Development and psychopathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

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  3. Family functioning and adolescent risk perception of opioid misuse: A cross-sectional study.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kit K ElamArizona State University.
Frances L WangArizona State University.
Kaitlin BountressMedical University of South Carolina.
Laurie ChassinArizona State University.
Danielle PandikaArizona State University.
Kathryn Lemery-ChalfantArizona State University.
Arizona State University · USMedical University of South Carolina · US

Funding

Resource CoreP60AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI TRULL, TIMOTHY J · 2009 to 2013
$8.8M
Research training in substance use prevention: Closing the research-practice gapT32DA039772 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Cady Berkel, Nancy A. Gonzales · 2015 to 2026
$4.2M
Training in Child Mental Health/Primary PreventionT32MH018387 · NIMH · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 1987 to 2014
$3.8M
Substance Use Among Children of AlcoholicsR01AA016213 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 2006 to 2010
$3.1M
SUBSTANCE USE AMONG YOUNG ADULT CHILDREN OF ALCOHOLICSR01DA005227 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 1987 to 2003
$2.2M
Exploring a novel approach to clarify parenting effects on drinking outcomesR21AA022097 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 2013 to 2014
$382k
Serotonin Genes and Adolescent Alcohol and Drug Involvement:Mechanisms of RiskF31AA023128 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WANG, FRANCES L · 2014 to 2016
$108k
Parent and Peer Influences on Alcohol Use Problems: A Genetically Informed StudyF31AA021612 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI BOUNTRESS, KAITLIN ELIZABETH · 2012 to 2013
$75k
NIAAA NIH HHS F31 AA021612NIAAA NIH HHS F31 AA023128NIAAA NIH HHS P60 AA011998NIAAA NIH HHS R01 AA016213NIAAA NIH HHS R21 AA022097NIDA NIH HHS R01 DA005227NIDA NIH HHS T32 DA039772NIMH NIH HHS T32 MH018387
6 · The paper itself

Abstract

Deviance proneness models propose a multilevel interplay in which transactions among genetic, individual, and family risk factors place children at increased risk for substance use. We examined bidirectional transactions between impulsivity and family conflict from middle childhood to adolescence and their contributions to substance use in adolescence and emerging adulthood (n = 380). Moreover, we examined children's, mothers', and fathers' polygenic risk scores for behavioral undercontrol, and mothers' and fathers' interparental conflict and substance disorder diagnoses as predictors of these transactions. The results support a developmental cascade model in which children's polygenic risk scores predicted greater impulsivity in middle childhood. Impulsivity in middle childhood predicted greater family conflict in late childhood, which in turn predicted greater impulsivity in late adolescence. Adolescent impulsivity subsequently predicted greater substance use in emerging adulthood. Results are discussed with respect to evocative genotype-environment correlations within developmental cascades and applications to prevention efforts.

Indexed as

Impulsive BehaviorAdolescentChildFamily ConflictFemaleHumansMaleParentsRisk FactorsSubstance-Related Disorders

Identifiers

PMID27427799
PMCPMC4955880
OpenAlexW2489191490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.