ArticleScientific reports2016
Topographical functional connectivity patterns exist in the congenitally, prelingually deaf.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 39 citations in OpenAlex.
- Mechanisms driving the functional maturation of the developing mammalian auditory pathway.Current topics in developmental biology · 2025Review
- Longitudinal stability of individual brain plasticity patterns in blindness.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A Whole-Brain Topographic Ontology.Annual review of neuroscience · 2024Review
- Priming central sound processing circuits through induction of spontaneous activity in the cochlea before hearing onset.Trends in neurosciences · 2024Review
- Temporal visual representation elicits early auditory-like responses in hearing but not in deaf individuals.Scientific reports · 2022Article
- Auditory cortical stimulability in non habilitated individuals - An evidence from CAEPs.Journal of otology · 2022Article
- Individual Variability in Functional Organization of the Human and Monkey Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Close yet independent: Dissociation of social from valence and abstract semantic dimensions in the left anterior temporal lobe.Human brain mapping · 2019Article
- Abnormal auditory tonotopy in patients with schizophrenia.NPJ schizophrenia · 2019Article
- Plasticity based on compensatory effector use in the association but not primary sensorimotor cortex of people born without hands.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Evaluation of Cerebral White Matter in Prelingually Deaf Children Using Diffusion Tensor Imaging.BioMed research international · 2018Article
- Task-specific reorganization of the auditory cortex in deaf humans.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
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Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital deafness causes large changes in the auditory cortex structure and function, such that without early childhood cochlear-implant, profoundly deaf children do not develop intact, high-level, auditory functions. But how is auditory cortex organization affected by congenital, prelingual, and long standing deafness? Does the large-scale topographical organization of the auditory cortex develop in people deaf from birth? And is it retained despite cross-modal plasticity? We identified, using fMRI, topographic tonotopy-based functional connectivity (FC) structure in humans in the core auditory cortex, its extending tonotopic gradients in the belt and even beyond that. These regions show similar FC structure in the congenitally deaf throughout the auditory cortex, including in the language areas. The topographic FC pattern can be identified reliably in the vast majority of the deaf, at the single subject level, despite the absence of hearing-aid use and poor oral language skills. These findings suggest that large-scale tonotopic-based FC does not require sensory experience to develop, and is retained despite life-long auditory deprivation and cross-modal plasticity. Furthermore, as the topographic FC is retained to varying degrees among the deaf subjects, it may serve to predict the potential for auditory rehabilitation using cochlear implants in individual subjects.
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