ArticleNature communications2016
A transgenic approach for controlling Lygus in cotton.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Bt agave: why it is time to explore a new biotechnological frontier.Pest management science · 2026Review
- Basic Research on Whitefly Molecular Biology: A Foundation for Innovative Pest Management Strategies.Current issues in molecular biology · 2026Review
- Breeding and Molecular Characterization of Insect-Resistant Transgenic Cotton.Plants (Basel, Switzerland) · 2026Article
- Article
- Prey-mediated effects of Mpp51Aa2-producing cotton on longevity and reproduction of Orius majusculus.Transgenic research · 2024Article
- Evaluation of Cotton Fleahopper (Insects · 2024Article
- Field Evaluation of Cotton Expressing Mpp51Aa2 as a Management Tool for Cotton Fleahoppers,Toxins · 2023Article
- Using Sentinel Plots to Monitor for Changes in Thrips Susceptibility to MON 88702 Cotton Containing the Cry51Aa2.834_16Insects · 2023Article
- The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity.Communications biology · 2022Article
- Peptide mediated, enhanced toxicity of a bacterial pesticidal protein against southern green stink bug.Microbial biotechnology · 2022Article
- Safety assessment of Mpp75Aa1.1, a new ETX_MTX2 protein from Brevibacillus laterosporus that controls western corn rootworm.PloS one · 2022Article
- Biotechnological Approaches for Host Plant Resistance to Insect Pests.Frontiers in genetics · 2022Review
- Can (We Make)Toxins · 2021Review
- Article
- Genetic engineering of crops for insect resistance: An overview.Journal of biosciences · 2020Article
- Transgenic crops for the agricultural improvement in Pakistan: a perspective of environmental stresses and the current status of genetically modified crops.GM crops & food · 2020Review
- Bacillus thuringiensis Cry1Da_7 and Cry1B.868 Protein Interactions with Novel Receptors Allow Control of Resistant Fall Armyworms, Spodoptera frugiperda (J.E. Smith).Applied and environmental microbiology · 2019Article
- Behavioral Responses of Thrips (Thysanoptera: Thripidae) and Tarnished Plant Bug (Hemiptera: Miridae) to a New Bt Toxin, Cry51Aa2.834_16 in Cotton.Journal of economic entomology · 2019Article
- Toxicity ofToxins · 2019Article
- Recent progress on the interaction between insects and Bacillus thuringiensis crops.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lygus species of plant-feeding insects have emerged as economically important pests of cotton in the United States. These species are not controlled by commercial Bacillus thuringiensis (Bt) cotton varieties resulting in economic losses and increased application of insecticide. Previously, a Bt crystal protein (Cry51Aa2) was reported with insecticidal activity against Lygus spp. However, transgenic cotton plants expressing this protein did not exhibit effective protection from Lygus feeding damage. Here we employ various optimization strategies, informed in part by protein crystallography and modelling, to identify limited amino-acid substitutions in Cry51Aa2 that increase insecticidal activity towards Lygus spp. by >200-fold. Transgenic cotton expressing the variant protein, Cry51Aa2.834_16, reduce populations of Lygus spp. up to 30-fold in whole-plant caged field trials. One transgenic event, designated MON88702, has been selected for further development of cotton varieties that could potentially reduce or eliminate insecticide application for control of Lygus and the associated environmental impacts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.