Evidence map›Paper›PMID 27425029›Full record

ArticleBiochimica et biophysica acta2016

Method for measuring the unbinding energy of strongly-bound membrane-associated proteins.

Elisa La Bauve, Briana C Vernon, Dongmei Ye, David M Rogers, Cathryn M Siegrist, Bryan D Carson, Susan B Rempe, Aihua Zheng, Margaret Kielian, Andrew P Shreve and 1 more

Abstract read
In one paragraph

Article in Biochimica et biophysica acta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisa La Bauve *Sandia National Laboratories, Albuquerque, NM 87185.
Briana C Vernon *Sandia National Laboratories, Albuquerque, NM 87185.
Dongmei YeSandia National Laboratories, Albuquerque, NM 87185.
David M RogersDepartment of Chemistry, University of South Florida, 4202 E Fowler Av, Tampa, FL 33620.
Cathryn M SiegristSandia National Laboratories, Albuquerque, NM 87185.
Bryan D CarsonSandia National Laboratories, Albuquerque, NM 87185.
Susan B RempeSandia National Laboratories, Albuquerque, NM 87185.
Aihua ZhengDepartment of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461.
Margaret KielianDepartment of Cell Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461.
Andrew P ShreveCenter for Biomedical Engineering and Department of Chemical and Biological Engineering, University of New Mexico, Albuquerque, NM 87131.
Michael S KentSandia National Laboratories, Albuquerque, NM 87185.

Funding

Molecular Analysis of Alphavirus Membrane Fusion ProteinR01AI075647 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KIELIAN, MARGARET · 2007 to 2023
$9.0M
NIAID NIH HHS R01 AI075647
6 · The paper itself

Abstract

We describe a new method to measure the activation energy for unbinding (enthalpy ΔH*

Indexed as

AnimalsCells, CulturedDengue VirusDrosophila melanogasterHydrogen-Ion ConcentrationKineticsLipid BilayersPhosphatidylcholinesPhosphatidylglycerolsProtein BindingThermodynamicsUnilamellar LiposomesViral Envelope Proteins1-palmitoyl-2-oleoylglycero-3-phosphoglycerol1-palmitoyl-2-oleoylphosphatidylcholineLipid BilayersPhosphatidylcholinesPhosphatidylglycerolsUnilamellar LiposomesViral Envelope ProteinsBinding energyDengue virus envelope proteinIntegral monotopic proteinsLipid membrane-associated proteinsLiposome–protein coflotation/sedimentationUnbinding energy

Identifiers

PMID27425029
PMCPMC5266593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.