Evidence map›Paper›PMID 27423911›Full record

ArticleThe ocular surface2016

Multiple Natural and Experimental Inflammatory Rabbit Lacrimal Gland Phenotypes.

Austin K Mircheff, Yanru Wang, Joel E Schechter, Meng Li, Warren Tong, Mayssa Attar, Murty Chengalvala, Joe Harmuth, Jeffery J Prusakiewicz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The ocular surface, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Autologous blood in the management of ocular surface disorders.World journal of experimental medicine · 2024
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Austin K MircheffDepartment of Physiology & Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: amirchef@usc.edu.
Yanru WangDepartment of Physiology & Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Joel E SchechterDepartment of Cell & Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Meng LiBioinformatics Service, Norris Medical Library, University of Southern California, Los Angeles, CA, USA.
Warren TongTranslational Drug Metabolism, Pharmacokinetics and Immunology, Allergan Inc., Irvine, CA, USA.
Mayssa AttarTranslational Drug Metabolism, Pharmacokinetics and Immunology, Allergan Inc., Irvine, CA, USA.
Murty ChengalvalaImmunology Services, Covance Research Products, Denver, PA, USA.
Joe HarmuthImmunology Services, Covance Research Products, Denver, PA, USA.
Jeffery J PrusakiewiczDrug Metabolism, Covance Laboratories Inc., Madison, WI, USA.

Funding

USC RESEARCH CENTER FOR LIVER DISEASES: PILOT PROGRAMSP30DK048522 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OOKHTENS, MURAD · 1995 to 2020
$21.8M
NIDDK NIH HHS P30 DK048522
6 · The paper itself

Abstract

purposeTo investigate lacrimal gland (LG) immunophysiological and immune-mediated inflammatory process (IMIP) phenotype diversity.

methodsEx vivo matured dendritic cells (mDC) were loaded with acinar cell microparticles (M

resultsImmunizing P

conclusionsThe underlying variability of normal states may contribute to the diversity of experimental IMIP phenotypes. The ability to generate and characterize diverse phenotypes may lead to phenotype-specific diagnostic and therapeutic paradigms.

Indexed as

Disease Models, AnimalAdoptive TransferAnimalsAutoantibodiesAutoantigensAutoimmunityBlotting, WesternDacryocystitisDendritic CellsEnzyme-Linked Immunosorbent AssayFemaleImmunoglobulin GImmunophenotypingLacrimal ApparatusLymphocyte ActivationPrincipal Component AnalysisAutoantibodiesAutoantigensImmunoglobulin GRose Bengalacinar cellsautoantigensdacryoadenitisdendritic cellsdry eyekeratoconjunctivitisSjögren disease

Identifiers

PMID27423911
PMCPMC5065763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.