Evidence map›Paper›PMID 27423367›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2016

Ambulatory Status Protects against Venous Thromboembolism in Acute Mild Ischemic Stroke Patients.

Jason-Flor V Sisante, Michael G Abraham, Milind A Phadnis, Sandra A Billinger, Manoj K Mittal

Abstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. The Association Between Stroke Mortality and Time of Admission and Participation in a Telestroke Network.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jason-Flor V SisanteDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas.
Michael G AbrahamDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas; Department of Radiology, University of Kansas Medical Center, Kansas City, Kansas.
Milind A PhadnisDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas.
Sandra A BillingerDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas.
Manoj K MittalDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas. Electronic address: mmittal2@kumc.edu.

Funding

Kansas University Training Program in Neurological and Rehabilitation SciencesT32HD057850 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jacob J. Sosnoff · 2009 to 2026
$3.4M
Examining Vascular Regulation Following Acute StrokeK01HD067318 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BILLINGER, SANDRA A · 2011 to 2015
$505k
NICHD NIH HHS K01 HD067318NICHD NIH HHS T32 HD057850
6 · The paper itself

Abstract

introductionIschemic stroke patients are at high risk (up to 18%) for venous thromboembolism. We conducted a retrospective cross-sectional study to understand the predictors of acute postmild ischemic stroke patient's ambulatory status and its relationship with venous thromboembolism, hospital length of stay, and in-hospital mortality.

methodsWe identified 522 patients between February 2006 and May 2014 and collected data about patient demographics, admission NIHSS (National Institutes of Health Stroke Scale), venous thromboembolism prophylaxis, ambulatory status, diagnosis of venous thromboembolism, and hospital outcomes (length of stay, mortality). Chi-square test, t-test and Wilcoxon rank-sum test, and binary logistic regression were used for statistical analysis as appropriate.

resultsA total of 61 (11.7%), 48 (9.2%), and 23 (4.4%) mild ischemic stroke patients developed venous thromboembolism, deep venous thrombosis, and pulmonary embolism, respectively. During hospitalization, 281 (53.8%) patients were ambulatory. Independent predictors of in-hospital ambulation were being married (OR 1.64, 95% CI 1.10-2.49), being nonreligious (OR 2.19, 95% CI 1.34-3.62), admission NIHSS (per unit decrease in NIHSS; OR 1.62, 95% CI 1.39-1.91), and nonuse of mechanical venous thromboembolism prophylaxis (OR 1.62, 95% CI 1.02-2.61). After adjusting for confounders, ambulatory patients had lower rates of venous thromboembolism (OR .47, 95% CI .25-.89), deep venous thrombosis (OR .36, 95% CI .17-.73), prolonged length of hospital stay (OR .24, 95% CI .16-.37), and mortality (OR .43, 95% CI .21-.84).

conclusionsOur findings suggest that for hospitalized acute mild ischemic stroke patients, ambulatory status is an independent predictor of venous thromboembolism (specifically deep venous thrombosis), hospital length of stay, and in-hospital mortality.

Indexed as

Mobility LimitationAgedBrain IschemiaChi-Square DistributionCross-Sectional StudiesDisability EvaluationFemaleHealth StatusHospital MortalityHumansLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds Ratioambulationambulatory statusdeep vein thrombosisIschemic strokeodds ratioprotectionpulmonary embolismvenous thromboembolism

Identifiers

PMID27423367
PMCPMC5201103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.