Evidence map›Paper›PMID 27423125›Full record

ReviewCurrent opinion in plant biology2016

Dynamic and diverse sugar signaling.

Lei Li, Jen Sheen

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in plant biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
53.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 294 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Sugar-sensing swodkoreceptors and swodkocrine signaling.Animal models and experimental medicine · 2025
    Article
  14. Article
  15. Review
  16. Metabolic plasticity and adaptive evolution inFrontiers in plant science · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lei LiDepartment of Genetics, Harvard Medical School, USA; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, MA 02114, USA.
Jen SheenDepartment of Genetics, Harvard Medical School, USA; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, MA 02114, USA. Electronic address: sheen@molbio.mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

Glucose Signal Transduction Pathways in PlantsR01GM060493 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2000 to 2017
$5.7M
Signaling Mechanisms in Plant Innate ImmunityR01GM070567 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2005 to 2017
$4.2M
NIGMS NIH HHS R01 GM060493NIGMS NIH HHS R01 GM070567
6 · The paper itself

Abstract

Sugars fuel life and exert numerous regulatory actions that are fundamental to all life forms. There are two principal mechanisms underlie sugar 'perception and signal transduction' in biological systems. Direct sensing and signaling is triggered via sugar-binding sensors with a broad range of affinity and specificity, whereas sugar-derived bioenergetic molecules and metabolites modulate signaling proteins and indirectly relay sugar signals. This review discusses the emerging sugar signals and potential sugar sensors discovered in plant systems. The findings leading to informative understanding of physiological regulation by sugars are considered and assessed. Comparative transcriptome analyses highlight the primary and dynamic sugar responses and reveal the convergent and specific regulators of key biological processes in the sugar-signaling network.

Indexed as

Carbohydrate MetabolismGene Expression Regulation, PlantSignal TransductionTranscriptomeArabidopsisPlant ProteinsPlant Proteins

Identifiers

PMID27423125
PMCPMC5050104
OpenAlexW2465269159

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.