ArticleInternational journal of clinical oncology2017
Sarcopenia predicts survival outcomes among patients with urothelial carcinoma of the upper urinary tract undergoing radical nephroureterectomy: a retrospective multi-institution study.
Article in International journal of clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Pre-Therapeutic Sarcopenia among Cancer Patients: An Up-to-Date Meta-Analysis of Prevalence and Predictive Value during Cancer Treatment.Nutrients · 2023Pooled it
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- Sarcopenia is associated with survival in patients with urothelial carcinoma treated with systemic chemotherapy.International journal of clinical oncology · 2022Article
- Impact of Preoperative Malnutrition on Postoperative Long-Term Outcomes of Patients With Pancreatic Head Cancer.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021Article
- The effect of different measurement modalities in the association of lean mass with mortality: A systematic review and meta-analysis.Osteoporosis and sarcopenia · 2021Article
- Systematic review and meta-analysis of lean mass and mortality: Rationale and study description.Osteoporosis and sarcopenia · 2021Article
- Impact of cachexia on oncologic outcomes of sarcopenic patients with upper tract urothelial carcinoma after radical nephroureterectomy.PloS one · 2021Article
- Computed Tomography-Based Body Composition in Patients With Ovarian Cancer: Association With Chemotoxicity and Prognosis.Frontiers in oncology · 2021Article
- Sarcopenia as a significant predictive factor of neutropenia and overall survival in urothelial carcinoma patients underwent gemcitabine and cisplatin or carboplatin.International journal of clinical oncology · 2020Article
- Metabolic and Molecular Basis of Sarcopenia: Implications in the Management of Urothelial Carcinoma.International journal of molecular sciences · 2019Review
- Effect of Changes in Skeletal Muscle Mass on Oncological Outcomes During First-Line Sunitinib Therapy for Metastatic Renal Cell Carcinoma.Targeted oncology · 2018Article
- Implications of low muscle mass across the continuum of care: a narrative review.Annals of medicine · 2018Review
- Sarcopenia as a comorbidity-independent predictor of survival following radical cystectomy for bladder cancer.Journal of cachexia, sarcopenia and muscle · 2018Article
- Preoperative sarcopenia status is associated with lymphovascular invasion in upper tract urothelial carcinoma patients treated with radical nephroureterectomy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018Article
- Article
- Impact of Sarcopenia in Patients with Unresectable Locally Advanced Esophageal Cancer Receiving Chemoradiotherapy.In vivo (Athens, Greece)Article
- The Controlling Nutritional Status CONUT Score in Patients With Advanced Bladder Cancer After Radical Cystectomy.In vivo (Athens, Greece)Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to evaluate the effect of sarcopenia, a condition of low muscle mass, on the survival among patients who were undergoing radical nephroureterectomy (RNU) for urothelial carcinoma of the upper urinary tract (UCUT).
methodsWe retrospectively reviewed consecutive patients with UCUT (cT[any]N0M0) who underwent RNU between 2003 and 2013 at our department and its affiliated institutions. Preoperative computed tomography images were used to calculate each patient's skeletal muscle index, an indicator of whole-body muscle mass. Sarcopenia was defined according to the sex-specific consensus definitions, based on the patient's skeletal muscle and body mass indexes. We analyzed the relapse-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) after RNU to identify factors that predicted patient survival.
resultsA total of 137 patients were included, and 90 patients (65.7 %) were diagnosed with sarcopenia. Compared to the non-sarcopenic patients, the sarcopenic patients had a significant inferior 5-year RFS (48.8 vs. 79.6 %, p = 0.0002), CSS (57.1 vs. 92.6 %, p < 0.0001), and OS (48.2 vs. 90.6 %, p < 0.0001). Multivariate analyses revealed that sarcopenia was an independent predictor of shorter RFS, CSS, and OS (all, p < 0.0001).
conclusionsSarcopenia was an independent predictor of survival among patients with UCUT who were undergoing RNU.
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