Evidence map›Paper›PMID 27421582›Full record

ArticleReproductive toxicology (Elmsford, N.Y.)2016

Roles of ion channels in regulation of acetylcholine-mediated vasoconstrictions in umbilical cords of rabbit/rats.

Zhoufeng Zhu, Jiaqi Tang, Xiuwen Zhou, Sharon Xiang, Xiaolin Zhu, Na Li, Ruixiu Shi, Yuan Zhong, Lubo Zhang, Miao Sun and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive toxicology (Elmsford, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Zhoufeng ZhuInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Jiaqi TangInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Xiuwen ZhouInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Sharon XiangInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China; Center for Perinatal Biology, Loma Linda University, Loma Linda, CA, USA.
Xiaolin ZhuInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Na LiInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Ruixiu ShiInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Yuan ZhongInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Lubo ZhangCenter for Perinatal Biology, Loma Linda University, Loma Linda, CA, USA.
Miao SunInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China. Electronic address: miaosunsuda@163.com.
Zhice XuInstitute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China; Center for Perinatal Biology, Loma Linda University, Loma Linda, CA, USA. Electronic address: xuzhice@suda.edu.cn.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNLoma Linda University · US

Funding

Developmental Programming of Ischemic-Sensitive Phenotype in the HeartR01HL118861 · NHLBI · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 2014 to 2017
$1.8M
NHLBI NIH HHS R01 HL118861
6 · The paper itself

Abstract

We recently demonstrated that acetylcholine (ACh) produced reliable vasoconstrictions in the umbilical cords. This study investigated the possible mechanisms with different antagonists. ACh-mediated vasoconstrictions were decreased by voltage-operated calcium (Ca

Indexed as

AcetylcholineAnimalsCalciumCalcium Channel BlockersCalcium ChannelsCarotid ArteriesCholinergic AgonistsFemaleIn Vitro TechniquesMyocytes, Smooth MusclePotassium Channel BlockersPotassium ChannelsPregnancyRabbitsRats, Sprague-DawleyUmbilical CordAcetylcholineCalciumCalcium Channel BlockersCalcium ChannelsCholinergic AgonistsPotassium Channel BlockersPotassium ChannelsAcetylcholineCalcium channelPotassium channelUmbilical cord

Identifiers

PMID27421582
PMCPMC5638043
OpenAlexW2471497124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.