Evidence map›Paper›PMID 27421291›Full record

ReviewExperimental brain research2016

Neuromechanical interactions between the limbs during human locomotion: an evolutionary perspective with translation to rehabilitation.

E P Zehr, Trevor S Barss, Katie Dragert, Alain Frigon, Erin V Vasudevan, Carlos Haridas, Sandra Hundza, Chelsea Kaupp, Taryn Klarner, Marc Klimstra and 6 more

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Experimental brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

E P ZehrRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1. pzehr@uvic.ca.
Trevor S BarssRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Katie DragertRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Alain FrigonDepartment of Pharmacology-physiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada.
Erin V VasudevanDepartment of Physical Therapy, SUNY Stony Brook University, Stony Brook, NY, USA.
Carlos HaridasRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Sandra HundzaHuman Discovery Science, International Collaboration on Repair Discoveries (ICORD), Vancouver, BC, Canada.
Chelsea KauppRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Taryn KlarnerRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Marc KlimstraCentre for Biomedical Research, University of Victoria, Victoria, BC, Canada.
Tomoyoshi KomiyamaDivision of Sports and Health Science, Chiba University, Chiba, Japan.
Pamela M LoadmanRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Rinaldo A MezzaraneLaboratory of Signal Processing and Motor Control, College of Physical Education, Universidade de Brasília-UnB, Brasília, Brazil.
Tsuyoshi NakajimaDepartment of Integrative Physiology, Kyorin University School of Medicine, Tokyo, Japan.
Gregory E P PearceyRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
Yao SunRehabilitation Neuroscience Laboratory, University of Victoria, PO Box 3010 STN CSC, Victoria, BC, Canada, V8W 3P1.
University of Victoria · CAChiba University · JPInternational Collaboration On Repair Discoveries · CAKyorin University · JPStony Brook University · USUniversidade de Brasília · BRUniversité de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During bipedal locomotor activities, humans use elements of quadrupedal neuronal limb control. Evolutionary constraints can help inform the historical ancestry for preservation of these core control elements support transfer of the huge body of quadrupedal non-human animal literature to human rehabilitation. In particular, this has translational applications for neurological rehabilitation after neurotrauma where interlimb coordination is lost or compromised. The present state of the field supports including arm activity in addition to leg activity as a component of gait retraining after neurotrauma.

Indexed as

Biological EvolutionTranslational Research, BiomedicalAnimalsBrain DiseasesExtremitiesGait Disorders, NeurologicHumansLocomotionCNSEvolutionNeurosciencePrimateReflexRehabilitationWalking

Identifiers

PMID27421291
PMCPMC5071371
OpenAlexW2465343644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.