ReviewCNS neuroscience & therapeutics2016
Sleep and Pain in Pediatric Illness: A Conceptual Review.
Review in CNS neuroscience & therapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05164354 (The Effect of Cancer Therapy and Music Concert Applied to Children on Sleep), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Cancer Therapy and Music Concert Applied to Children on Sleep
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Efficacy of psychological interventions on sleep in children and adolescents with chronic pain: a systematic review with meta-analysis of randomized controlled trials.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Pooled it
- Sleep disorders in cystic fibrosis: A systematic review and meta-analysis.Sleep medicine reviews · 2020Pooled it
- Moderators of Internet-Delivered Cognitive-Behavioral Therapy for Adolescents With Chronic Pain: Who Benefits From Treatment at Long-Term Follow-Up?The journal of painTrial
- Psychosocial burden in pediatric familial mediterranean fever: A study of quality of life, sleep habits, maternal mental health, and clinical correlates.BMC psychology · 2026Article
- Polysomnography demonstrates worse sleep in children and adolescents with disorders of gut-brain interaction (DGBI) compared to healthy children: A case-control study.Sleep medicine · 2026Article
- Targeting the Medial Prefrontal Cortex with Transcranial Focused Ultrasound Alleviates Adolescent Sleep-Deprivation-Induced Persistent Postsurgical Pain in Adulthood.Research (Washington, D.C.) · 2026Article
- Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence.Journal of adolescence · 2026Article
- Sleep Disturbances and Disorders in Children and Adolescents with Cerebral Palsy: A Narrative Review.Journal of clinical medicine · 2025Review
- Youth With Functional Abdominal Pain Disorders Have More Sleep Disturbances. A School-Based Study.Neurogastroenterology and motility · 2025Article
- Comparison of actigraphy with a sleep protocol maintained by professional caregivers and questionnaire-based parental judgment in children and adolescents with life-limiting conditions.BMC palliative care · 2024Article
- Sleep-Disordered Breathing and Chronic Respiratory Infections: A Narrative Review in Adult and Pediatric Population.International journal of molecular sciences · 2023Review
- The complexities of the sleep-pain relationship in adolescents: A critical review.Sleep medicine reviews · 2023Review
- Applicability of Actigraphy for Assessing Sleep Behaviour in Children with Palliative Care Needs Benchmarked against the Gold Standard Polysomnography.Journal of clinical medicine · 2022Article
- Shedding Light on the Lifestyle and Participation of Portuguese Adolescents with Chronic Conditions-Data from the HBSC 2018 Study.Children (Basel, Switzerland) · 2022Article
- Pediatric sleep and pain: etiologies, consequences, and clinical considerations.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Review
- Sleep in children with cystic fibrosis: More under the covers.Pediatric pulmonology · 2022Review
- Sleep phase and pre-sleep arousal predicted co-developmental trajectories of pain and insomnia within adolescence.Scientific reports · 2022Article
- Associations of frequent pain symptoms with excessive daytime sleepiness in adolescents: a longitudinal study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Prevalence of Sleep Disturbances in Pediatric Cancer Patients and Their Diagnosis and Management.Children (Basel, Switzerland) · 2021Review
- Pediatric sickle cell pain-sleep relationships: The roles of positive and negative affect.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleep disruption is a common comorbidity of pediatric pain. Consequences of pain and disrupted sleep, evidence for the pain-sleep relation, and how aspects of illness, treatment, and pharmacological pain management may contribute to or exacerbate these issues are presented.
aimsThis conceptual review explored the relation between pain and sleep in children diagnosed with chronic medical or developmental conditions. The goal of this review is to expand upon the literature by examining common themes in sleep disturbances associated with painful conditions across multiple pediatric illnesses. Populations reviewed include youth with intellectual and developmental disabilities (IDD), migraines, cystic fibrosis (CF), sickle cell disease (SCD), cancer, juvenile idiopathic arthritis (JIA), juvenile fibromyalgia (JFM), and functional gastrointestinal disorders (FGIDs).
resultsConsistent evidence demonstrates that children with medical or developmental conditions are more vulnerable to experiencing pain and subjective sleep complaints than healthy peers. Objective sleep concerns are common but often under-studied. Evidence of the pain-sleep relationship exists, particularly in pediatric SCD, IDD, and JIA, with a dearth of studies directly examining this relation in pediatric cancer, JFM, CF, and FGIDs. Findings suggest that assessing and treating pain and sleep disruption is important when optimizing functional outcomes.
conclusionIt is essential that research further examine objective sleep, elucidate the pain-sleep relationship, consider physiological and psychosocial mechanisms of this relationship, and investigate nonpharmacological interventions aimed at improving pain and sleep in vulnerable pediatric populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.