Evidence map›Paper›PMID 27420900›Full record

ArticleRadiology2017

Cardiac Chemical Exchange Saturation Transfer MR Imaging Tracking of Cell Survival or Rejection in Mouse Models of Cell Therapy.

Ashley L Pumphrey, Shaojing Ye, Zhengshi Yang, Jennifer Simkin, John C Gensel, Ahmed Abdel-Latif, Moriel H Vandsburger

Open access · greenAbstract read
In one paragraph

Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  8. Optimized CEST cardiovascular magnetic resonance for assessment of metabolic activity in the heart.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ashley L PumphreyFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
Shaojing YeFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
Zhengshi YangFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
Jennifer SimkinFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
John C GenselFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.ORCID http://orcid.org/0000-0001-8980-108X
Ahmed Abdel-LatifFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
Moriel H VandsburgerFrom the Saha Cardiovascular Research Center (A.L.P., S.Y., Z.Y., A.A.L., M.H.V.) and Spinal Cord and Brain Injury Research Center (J.S., J.C.G.), University of Kentucky, 741 S Limestone St, BBSRB 355, Lexington, KY 40536.
University of Kentucky · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2012 to 2017
$13.7M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
Kentucky Center for Clinical and Translational ScienceKL2TR000116 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$1.9M
Novel MRI techniques for imaging cardiac fibrosis to improve clinical practice in patients with renal failureR01HL128592 · NHLBI · UNIVERSITY OF KENTUCKY · PI VANDSBURGER, MORIEL · 2015 to 2019
$1.9M
NCATS NIH HHS KL2 TR000116NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NHLBI NIH HHS R01 HL128592NIGMS NIH HHS P20 GM103527
6 · The paper itself

Abstract

Purpose To examine whether cardiac chemical exchange saturation transfer (CEST) imaging can be serially and noninvasively used to probe cell survival or rejection after intramyocardial implantation in mice. Materials and Methods Experiments were compliant with the National Institutes of Health Guidelines on the Use of Laboratory Animals and approved by the Institutional Animal Care and Use Committee. One million C2C12 cells labeled with either europium (Eu) 10-(2-hydroxypropyl)-1,4,7-tetraazacyclododecane-1,4,7-triacetic acid (HP-DO3A) or saline via the hypotonic swelling technique were implanted into the anterior-lateral left ventricular wall in C57BL/6J (allogeneic model, n = 17) and C3H (syngeneic model, n = 13) mice. Imaging (frequency offsets of ±15 parts per million) was performed 1, 10, and 20 days after implantation, with the asymmetrical magnetization transfer ratio (MTR

Indexed as

Cell- and Tissue-Based TherapyAnimalsCell ProliferationCell SurvivalCell TrackingElectrocardiographyGraft RejectionMagnetic Resonance Imaging, CineMaleMiceMice, Inbred C3HMice, Inbred C57BLModels, AnimalMyocardiumRespiratory-Gated Imaging TechniquesSignal-To-Noise Ratio

Identifiers

PMID27420900
PMCPMC5207119
OpenAlexW2468496093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.