Evidence map›Paper›PMID 27420399›Full record

ReviewRedox report : communications in free radical research2017

Mechanisms involved in the development of diabetic retinopathy induced by oxidative stress.

David Calderón Guzman, Hugo Juárez Olguín, Ernestina Hernández García, Armando Valenzuela Peraza, Diego Zamora de la Cruz, Monica Punzo Soto

Open access · bronzeAbstract readReview
In one paragraph

Review in Redox report : communications in free radical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Alleviate oxidative stress in diabetic retinopathy: antioxidant therapeutic strategies.Redox report : communications in free radical research · 2023
    Review
  6. Review
  7. Exploring the multifaceted role of TGF-β signaling in diabetic complications.Environmental science and pollution research international · 2022
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Therapeutic potential ofIranian journal of basic medical sciences · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

David Calderón Guzmana Laboratory of Neurochemistry , National Institute of Pediatrics , Mexico.
Hugo Juárez Olguínb Laboratory of Pharmacology , National Institute of Pediatrics , Mexico.
Ernestina Hernández Garcíab Laboratory of Pharmacology , National Institute of Pediatrics , Mexico.
Armando Valenzuela Perazaa Laboratory of Neurochemistry , National Institute of Pediatrics , Mexico.
Diego Zamora de la Cruzc Faculty of Medicine, Department of Pharmacology , National Autonomous University of Mexico , Mexico.
Monica Punzo Sotob Laboratory of Pharmacology , National Institute of Pediatrics , Mexico.
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic retinopathy (DR) is one of the main complications in patients with diabetes and has been the leading cause of visual loss since 1990. Oxidative stress is a biological process resulting from excessive production of reactive oxygen species (ROS). This process contributes to the development of many diseases and disease complications. ROS interact with various cellular components to induce cell injury. Fortunately, there is an antioxidan t system that protects organisms against ROS. Indeed, when ROS exceed antioxidant capacity, the resulting cell injury can cause diverse physiological and pathological changes that could lead to a disease like DR.

objectiveThis paper reviews the possible mechanisms of common and novel biomarkers involved in the development of DR and explores how these biomarkers could be used to monitor the damage induced by oxidative stress in DR, which is a significant complication in people with diabetes.

conclusionThe poor control of glucemy in pacients with DB has been shown contribute to the development of complications in eyes as DR.

Indexed as

AnimalsBiomarkersDiabetic RetinopathyHumansOxidative StressReactive Oxygen SpeciesRetinaBiomarkersReactive Oxygen SpeciesBiomarkersDiabetic retinopathyOxidative stressRetinal damage

Identifiers

PMID27420399
PMCPMC6837689
OpenAlexW2463503164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.