SynthesisInternational journal of environmental research and public health2016
Ambient Temperature and Stroke Occurrence: A Systematic Review and Meta-Analysis.
Synthesis in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Association between ambient temperature and risk of stroke morbidity and mortality: A systematic review and meta-analysis.Brain and behavior · 2023Pooled it
- Association between ambient temperature and stroke risk in high-risk populations: a systematic review.Frontiers in neurology · 2023Pooled it
- Seasonal variation in the occurrence of ischemic stroke: A meta-analysis.Environmental geochemistry and health · 2019Pooled it
- Non optimal temperatures and chronic cardiovascular diseases.Seminars in immunopathology · 2026Review
- Seasonal variation in inflammatory biomarkers and blood pressure among patients with ischemic stroke: the influence of clinical confounding factors.BMC neurology · 2026Article
- Cross sectional analysis of the association between extreme climate events and stroke incidence in middle aged and older Chinese adults.Scientific reports · 2025Article
- Temperature Exposure and Acute Cardiovascular Disease Risk in New York City: Case Time Series.Journal of the American Heart Association · 2025Article
- Article
- Interactive Effect of Air Temperature and Fine Particulate Matter on the Hospital Admissions for Stroke in Shenzhen, China.Journal of the American Heart Association · 2025Article
- The bleeding weather: association of environmental changes with intracranial aneurysms' rupture.Acta neurochirurgica · 2025Article
- Study on the relationship among typhoon, weather change and acute ischemic stroke in southern Zhejiang Province of China.BMC neurology · 2025Article
- Article
- Neurological and mental health in the era of climate change: mechanisms, clinical impacts, and adaptation.Frontiers in public health · 2025Review
- Prognostic significance of free triiodothyronine levels in alpine region patients undergoing drug-coated balloon therapy for coronary heart disease.Journal of cardiothoracic surgery · 2024Article
- Challenges posed by climate hazards to cardiovascular health and cardiac intensive care: implications for mitigation and adaptation.European heart journal. Acute cardiovascular care · 2024Review
- Climate Change and Aging: Implications for Psychiatric Care.Current psychiatry reports · 2024Review
- Air Pollution Increases Risk of Occurrence of Intracerebral Haemorrhage but Not of Subarachnoid Haemorrhage: Time-Series Cross-Sectional Study.Biomedicines · 2024Article
- Article
- Burden of Stroke Attributable to Nonoptimal Temperature in 204 Countries and Territories: A Population-Based Study, 1990-2019.Neurology · 2024Article
- Hourly Heat Exposure and Acute Ischemic Stroke.JAMA network open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 5 countries.
Funding
Abstract
Biologically plausible associations exist between climatic conditions and stroke risk, but study results are inconsistent. We aimed to summarize current evidence on ambient temperature and overall stroke occurrence, and by age, sex, and variation of temperature. We performed a systematic literature search across MEDLINE, Embase, PsycINFO, CINAHL, Web of Science, and GEOBASE, from inception to 16 October 2015 to identify all population-based observational studies. Where possible, data were pooled for meta-analysis with Odds ratios (OR) and corresponding 95% confidence intervals (CI) by means of the random effects meta-analysis. We included 21 studies with a total of 476,511 patients. The data were varied as indicated by significant heterogeneity across studies for both ischemic stroke (IS) and intracerebral hemorrhage (ICH). Pooled OR (95% CI) in every 1 degree Celsius increase in ambient temperature was significant for ICH 0.97 (0.94-1.00), but not for IS 1.00 (0.99-1.01) and subarachnoid hemorrhage (SAH) 1.00 (0.98-1.01). Meta-analysis was not possible for the pre-specified subgroup analyses by age, sex, and variation of temperature. Change in temperature over the previous 24 h appeared to be more important than absolute temperature in relation to the risk of stroke, especially in relation to the risk of ICH. Older age appeared to increase vulnerability to low temperature for both IS and ICH. To conclude, this review shows that lower mean ambient temperature is significantly associated with the risk of ICH, but not with IS and SAH. Larger temperature changes were associated with higher stroke rates in the elderly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.