ArticleThe ISME journal2017
Association mapping reveals novel serpentine adaptation gene clusters in a population of symbiotic Mesorhizobium.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Redundancy maintains microbial ecosystem functional potential despite taxonomic shifts between serpentine and nonserpentine soils.Microbial genomics · 2026Article
- Regulation of a nickel tolerance operon conserved inApplied and environmental microbiology · 2025Article
- Population Persistence and Soil Microbial Communities of a Serpentine Endemic Plant Outside Its Historic Elevation Range.Ecology and evolution · 2025Article
- The evolutionary genomics of adaptation to stress in wild rhizobium bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Population genomics of Australian indigenousMicrobial genomics · 2023Article
- Article
- Invasive Grass Dominance over Native Forbs Is Linked to Shifts in the Bacterial Rhizosphere Microbiome.Microbial ecology · 2022Article
- Horizontal gene transfer and adaptive evolution in bacteria.Nature reviews. Microbiology · 2022Review
- Environmental stress leads to genome streamlining in a widely distributed species of soil bacteria.The ISME journal · 2022Article
- Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen.Advances in experimental medicine and biology · 2022Article
- Recombination Facilitates Adaptive Evolution in Rhizobial Soil Bacteria.Molecular biology and evolution · 2021Article
- Spatial patterns in phage-Rhizobium coevolutionary interactions across regions of common bean domestication.The ISME journal · 2021Article
- Cryptic speciation of a pelagic Roseobacter population varying at a few thousand nucleotide sites.The ISME journal · 2020Article
- Symbiosis islands of Loteae-nodulatingMicrobial genomics · 2020Article
- Host-specific competitiveness to form nodules in Rhizobium leguminosarum symbiovar viciae.The New phytologist · 2020Article
- Dynamic genomic architecture of mutualistic cooperation in a wild population of Mesorhizobium.The ISME journal · 2019Article
- Review
- Genome-Wide Association Analyses in the Model RhizobiummSphere · 2018Article
- Phylogeny-corrected identification of microbial gene families relevant to human gut colonization.PLoS computational biology · 2018Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The genetic variants that underlie microbial environmental adaptation are key components of models of microbial diversification. Characterizing adaptive variants and the pangenomic context in which they evolve remains a frontier in understanding how microbial diversity is generated. The genomics of rhizobium adaptation to contrasting soil environments is ecologically and agriculturally important because these bacteria are responsible for half of all current biologically fixed nitrogen, yet they live the majority of their lives in soil. Our study uses whole-genome sequencing to describe the pan-genome of a focal clade of wild mesorhizobia that show contrasting levels of nickel adaptation despite high relatedness (99.8% identity at 16S). We observe ecotypic specialization within an otherwise genomically cohesive population, rather than finding distinct specialized bacterial lineages in contrasting soil types. This finding supports recent reports that heterogeneous environments impose selection that maintains differentiation only at a small fraction of the genome. Our work further uses a genome-wide association study to propose candidate genes for nickel adaptation. Several candidates show homology to genetic systems involved in nickel tolerance and one cluster of candidates correlates perfectly with soil origin, which validates our approach of ascribing genomic variation to adaptive divergence.
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